ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2025
Loop gain and central chemosensitivity assessment as a valuable tool in guiding treatment decisions for central sleep apnea in children.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Age-dependent dissociation between sleep-disordered breathing severity and ventilatory impairment in children with Prader-Willi syndrome.Frontiers in pediatrics · 2026Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
citationThis study presents 2 cases of central sleep apnea syndrome in children, highlighting the utility of assessing ventilatory control stability, particularly loop gain and central chemosensitivity in treatment decision-making. In the first case, elevated loop gain for oxygen correlated with periodic breathing, leading to successful treatment with supplemental oxygen in a 13-year-old male with Prader-Willi-like syndrome. Conversely, in the second case, dealing with a 10-year-old female with tumor in the brainstem-spinal cord junction, reduced loop gain prompted treatment with nocturnal noninvasive ventilation. These findings underscore the potential clinical relevance of loop gain measurement in pediatric central sleep apnea. While further research is needed to validate these findings in larger cohorts, loop gain endotyping shows promise as a tool for personalized treatment selection in pediatric sleep-disordered breathing. CITATION: Bokov P, Dudoignon B, Delclaux C. Loop gain and central chemosensitivity assessment as a valuable tool in guiding treatment decisions for central sleep apnea in children.
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