ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2025
Adherence to positive airway pressure therapy in patients with Down syndrome: assessing cloud-based monitoring data.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- How adherent are children with Down syndrome and obstructive sleep apnea to positive airway pressure therapy?Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- A Review of Clinical Trials in Down Syndrome.International review of research in developmental disabilities · 2025Article
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Authors and funding
7 authors.
Funding
Abstract
STUDY
objectivesObstructive sleep apnea is common in Down syndrome (DS) with many patients prescribed positive airway pressure (PAP) therapy. This study evaluates PAP adherence and identifies factors influencing adherence.
methodsRetrospective analysis of electronic health records and cloud-based PAP therapy data from patients with DS at Rady Children's Hospital, San Diego, CA. Cloud data were evaluated cross-sectionally at 30- and 90-night post-clinic visit and longitudinally in patients with ≥ 2 90-night data downloads. Outcomes included adherence (percentage of nights with ≥ 4 hours of use) and usage (percentage of nights with any PAP usage). The impact of demographic and PAP therapy factors (eg, mask leak) on these outcomes was also assessed.
resultsForty-seven patients with DS with cloud-based PAP therapy data over a 90-night period and 46 over a 30-night period were analyzed. The mean age was 17.7 ± 4.6 years (21 females). Median adherence was significantly higher at 30 nights (56.7%, interquartile range: 0.0, 90.8%) than at 90 nights (34.4%, interquartile range: 0.0, 86.7%) (
conclusionsCross-sectional and longitudinal analyses reveal that many patients with DS successfully adhere to PAP therapy, challenging the misconception that they struggle with adherence and proving they may be as successful, if not more, than non-DS patients. CITATION: Bhattacharjee R, Warner M, Nokes B, et al. Adherence to positive airway pressure therapy in patients with Down syndrome: assessing cloud-based monitoring data.
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