ArticleTherapeutic advances in cardiovascular disease
Outcomes among patients with coronary artery bypass grafts presenting with acute coronary syndrome: impact of revascularization.
Article in Therapeutic advances in cardiovascular disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Nationwide analysis of mortality predictors following in-hospital cardiac arrest in older Thai adults, 2016-2024.Resuscitation plus · 2026Article
- Association Between C-Reactive Protein-Triglyceride Glucose Index and Adverse Cardiovascular Outcomes in Acute Coronary Syndrome Patients With Prior Coronary Artery Bypass Grafting.Mediators of inflammation · 2026Article
- Review
- Prognostic significance of stress hyperglycemia ratio in acute coronary syndrome patients with prior coronary artery bypass grafting.Frontiers in endocrinology · 2025Article
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Authors and funding
10 authors.
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Abstract
backgroundPatients post-coronary artery bypass graft (CABG) can re-present with acute coronary syndrome (ACS); however, culprit lesion identification, as well as revascularization, is often challenging. Furthermore, the impact of revascularization in this patient group is relatively unknown.
objectivesThe purpose of our study was to evaluate the efficacy of percutaneous coronary intervention (PCI) in patients with previous CABG surgery presenting with ACS.
methodsUsing data from the Manitoba Center for Health Policy, we identified patients treated with CABG between April 1979 and March 2018, who subsequently presented with the primary diagnosis of ACS. Patients were divided into four groups: (1) managed medically and not investigated by cardiac catheterization and (2) investigated by cardiac catheterization and treated (2a) medically, (2b) with PCI, and (2c) with redo-CABG. Inverse probability treatment-weighted survival analyses were performed. Ethical approval was obtained from the local research board.
resultsNearly 20% of patients treated with CABG presented with ACS at a median of 7.2 years (age at the time of CABG: 66 years (interquartile range: 58-73 years); 75.6% male). Patients treated with PCI (
conclusionACS is not uncommon following CABG. Revascularization is associated with prognostic improvement; however, such could be accounted for by inherent group differences, including comorbidities and coronary anatomy These findings should be validated in a prospective randomized study.
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