Evidence map›Paper›PMID 39744832›Full record

ArticleDiabetes, obesity & metabolism2025

Predictive models of post-prandial glucose response in persons with prediabetes and early onset type 2 diabetes: A pilot study.

Leinys S Santos-Báez, Diana A Diaz-Rizzolo, Rabiah Borhan, Collin J Popp, Ana Sordi-Guth, Danny DeBonis, Emily N C Manoogian, Satchidananda Panda, Bin Cheng, Blandine Laferrère

Abstract read
In one paragraph

Article in Diabetes, obesity & metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Leinys S Santos-BáezDepartment of Medicine, Division of Endocrinology, Diabetes Research Center, Columbia University Irving Medical Center, New York, New York, USA.
Diana A Diaz-RizzoloDepartment of Medicine, Division of Endocrinology, Diabetes Research Center, Columbia University Irving Medical Center, New York, New York, USA.
Rabiah BorhanDepartment of Medicine, Division of Endocrinology, Diabetes Research Center, Columbia University Irving Medical Center, New York, New York, USA.
Collin J PoppDepartment of Population Health, New York Langone Health, New York, New York, USA.
Ana Sordi-GuthDepartment of Medicine, Division of Endocrinology, Diabetes Research Center, Columbia University Irving Medical Center, New York, New York, USA.
Danny DeBonisDepartment of Medicine, Division of Endocrinology, Diabetes Research Center, Columbia University Irving Medical Center, New York, New York, USA.
Emily N C ManoogianSalk Institute for Biological Studies, Regulatory Biology, La Jolla, California, USA.
Satchidananda PandaSalk Institute for Biological Studies, Regulatory Biology, La Jolla, California, USA.
Bin ChengDepartment of Biostatistics, Columbia University Irving Medical Center, New York, New York, USA.
Blandine LaferrèreDepartment of Medicine, Division of Endocrinology, Diabetes Research Center, Columbia University Irving Medical Center, New York, New York, USA.ORCID 0000-0001-8255-3175

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
RESEARCH TRAININGP30DK026687 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI Anthony W Ferrante, DYMPNA GALLAGHER · 1986 to 2026
$33.0M
Impact of Time-Restricted Feeding (TRF) on Glucose Homeostasis and Mitochondrial Function in Patients with Metabolic SyndromeR01DK118278 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Pam Rajendran Taub · 2018 to 2026
$5.3M
TREAT (Time Restricted EATing) to improve cardiometabolic healthR01AG065569 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LAFERRERE, BLANDINE B · 2020 to 2024
$3.9M
Personalized Dietary Management in Type 2 DiabetesR01NR018916 · NINR · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI POPP, COLLIN JEFFREY, SEGAL, ERAN · 2021 to 2025
$3.5M
Prolonged Daily Fasting As a Viable Alternative to Caloric Restriction in At-Risk Obese HumansR01DK124484 · NIDDK · UNIVERSITY OF MINNESOTA · PI CHOW, LISA SENYE · 2020 to 2023
$2.7M
Optimization of Chrononutrition to Reduce the Risk of Disease in Shift WorkersR01DK139356 · NIDDK · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Emily Nicole Corbett Manoogian · 2024 to 2026
$2.3M
Time Restricted Eating As a Viable Alternative to Caloric Restriction for Treating Hyperglycemia in a Population with Type 2 (T2DM) diabetesR01DK129668 · NIDDK · UNIVERSITY OF MINNESOTA · PI CHOW, LISA SENYE · 2022 to 2024
$949k
NCATS NIH HHS UL1 TR001873NIA NIH HHS R01 AG065569NIDDK NIH HHS P30 DK026687NIDDK NIH HHS R01 DK118278NIDDK NIH HHS R01 DK124484NIDDK NIH HHS R01 DK129668NIDDK NIH HHS R01 DK139356NIH HHS P30DK026687NIH HHS R01AG065569NIH HHS UL1TR001873NINR NIH HHS R01 NR018916
6 · The paper itself

Abstract

objectivePost-prandial glucose response (PPGR) is a risk factor for cardiovascular disease. Meal carbohydrate content is an important predictor of PPGR, but dietary interventions to mitigate PPGR are not always successful. A personalized approach, considering behaviour and habitual pattern of glucose excursions assessed by continuous glucose monitor (CGM), may be more effective. RESEARCH DESIGN AND

methodsData were collected under free-living conditions, over 2 weeks, in older adults (age 60 ± 7, BMI 33.0 ± 6.6 kg/m

resultsMean amplitude of glucose excursions (MAGE) and fasting glucose were highly predictive of all measures of OGTT-PPGR (AUC, peak, delta, mean glucose and glucose at 120 min; R

conclusionThese data support a CGM-guided personalized nutrition and medicine approach to control PPGR in older individuals with prediabetes and diet and/or metformin-treated type 2 diabetes.

Indexed as

Blood GlucoseDiabetes Mellitus, Type 2Postprandial PeriodPrediabetic StateAgedBlood Glucose Self-MonitoringFastingFemaleGlucose Tolerance TestHumansMaleMiddle AgedPilot ProjectsPredictive Value of TestsBlood Glucosecarbohydratesglucosepost‐prandial glucose responseprediabetes

Identifiers

PMID39744832
PMCPMC11802288

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.