ArticleCanadian journal of veterinary research = Revue canadienne de recherche veterinaire2025
Preliminary report: Protective effects of probiotics on cefovecin-induced gut dysbiosis in dogs.
Article in Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this study was to evaluate whether supplementation with probiotics over a 2-week period stabilizes the gut microbiota in dogs following prolonged cefovecin treatment. A significant number of clinical veterinarians prescribe oral probiotics to dogs in conjunction with systemic antibiotics with the intention of protecting against gut dysbiosis. The effects of antibiotics and probiotics in dogs have not been extensively studied, however, and the optimal treatment for gut dysbiosis remains uncertain. To investigate the impact of cefovecin and probiotics on the gut microbiota, 12 healthy companion dogs that underwent surgical castration were included in the study. The dogs were administered cefovecin immediately after surgery. Of the 12 dogs, 7 dogs were supplemented with oral probiotics for 2 wk after cefovecin treatment (probiotic group), whereas the other 5 dogs were not supplemented with probiotics (non-probiotic group). Fecal samples were collected from each dog before and 2 wk after cefovecin treatment and subjected to 16S rRNA gene sequencing using the Illumina platform. We noted that cefovecin induced changes in bacterial diversity of the gut microbiota, with the Shannon index values of the non-probiotic group decreasing significantly, whereas those of the probiotic group remained stable (
Indexed as
Identifiers
39744464PMC11665732What OpenQuestion holds
Registered trials
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