Evidence map›Paper›PMID 39744263›Full record

ReviewCureus2024

Sepsis in Aging Populations: A Review of Risk Factors, Diagnosis, and Management.

Abdulaziz H Alhamyani, Musharraf S Alamri, Nawwaf W Aljuaid, Abdulrhman H Aloubthani, Shafi Alzahrani, Ali A Alghamdi, Abdullah S Lajdam, Hamza Alamoudi, Abdulrahman A Alamoudi, Adham M Albulushi and 1 more

Abstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. ASP-COMPLEX: redefining antimicrobial stewardship to improve outcomes in high-risk patients with severe infections.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2026
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Abdulaziz H AlhamyaniFamily Medicine, Armed Forces Hospitals, Taif, SAU.
Musharraf S AlamriFamily Medicine, Armed Forces Hospitals, Taif, SAU.
Nawwaf W AljuaidFamily Medicine, Armed Forces Hospitals, Taif, SAU.
Abdulrhman H AloubthaniEmergency Medicine, King Abdulaziz University, Jeddah, SAU.
Shafi AlzahraniCardiology, King Fahad General Hospital, Al-Baha, SAU.
Ali A AlghamdiInternal Medicine, King Abdulaziz University, Jeddah, SAU.
Abdullah S LajdamInternal Medicine, King Abdulaziz University, Jeddah, SAU.
Hamza AlamoudiInternal Medicine, King Abdulaziz University, Jeddah, SAU.
Abdulrahman A AlamoudiInternal Medicine, King Abdulaziz University, Jeddah, SAU.
Adham M AlbulushiInternal Medicine, King Abdulaziz University, Jeddah, SAU.
Saad Nasser AlQarniInternal Medicine, Al-Baha University, Al-Baha, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis remains a significant global health concern, particularly among aging populations. This comprehensive review examines the complex interplay between aging and sepsis, focusing on risk factors, diagnostic challenges, and management strategies specific to older adults. The study explores the physiological changes associated with aging that contribute to increased sepsis susceptibility, including immunosenescence and chronic inflammation. It delves into the unique pathophysiology of sepsis in the elderly, highlighting the role of comorbidities and age-related immune dysfunction. The review emphasizes the importance of early recognition and tailored interventions for sepsis in older patients, addressing the often atypical presentation of symptoms in this population. By synthesizing current research and clinical guidelines, this study aims to enhance understanding of sepsis in aging populations and improve outcomes through targeted prevention, prompt diagnosis, and effective management strategies. The findings underscore the need for age-specific approaches in sepsis care and highlight areas for future research to address the growing burden of sepsis in an aging global population.

Indexed as

aging populationselderly caregeriatric medicineimmunosenescenceinflammagingseptic shock

Identifiers

PMID39744263
PMCPMC11691596

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.