Evidence map›Paper›PMID 39744240›Full record

ArticleFrontiers in nutrition2024

Effects of salt substitute on urinary electrolytes and blood pressure in a real-world setting-cohort study in Hunan, China.

Hao Wu, Wenbin Ouyang, Jing Deng, Yongmei He, Lu Yin, Xia Cao, Zhiheng Chen, Pingting Yang, Yaqin Wang, Ying Li and 1 more

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In one paragraph

Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hao WuDepartment of Health Management, The Third Xiangya Hospital, Central South University, Changsha, China.
Wenbin OuyangDepartment of Epidemiology, Hunan Normal University School of Medicine, Changsha, China.
Jing DengDepartment of Epidemiology, Xiangya School of Public Health, Central South University, Changsha, China.
Yongmei HeDepartment of Health Management, Aerospace Center Hospital, Beijing, China.
Lu YinMedical Research & Biometrics Center, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Xia CaoDepartment of Health Management, The Third Xiangya Hospital, Central South University, Changsha, China.
Zhiheng ChenDepartment of Health Management, The Third Xiangya Hospital, Central South University, Changsha, China.
Pingting YangDepartment of Health Management, The Third Xiangya Hospital, Central South University, Changsha, China.
Yaqin WangDepartment of Health Management, The Third Xiangya Hospital, Central South University, Changsha, China.
Ying LiDepartment of Health Management, The Third Xiangya Hospital, Central South University, Changsha, China.
Xin HuangDepartment of Epidemiology, Hunan Normal University School of Medicine, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Salt substitute is considered an effective strategy to reduce sodium and increase potassium intake and thereby lower blood pressure in China, but its benefits and risks are uncertain in real-world data. This study is designed to compare the difference in the 1-year efficacy of salt substitute and salt restriction on urinary electrolytes and blood pressure. Methods and results: A total of 2,929 and 2,071 participants with the 24-h estimated urinary sodium excretion (eUNaE) above 2.36 g/d using salt substitute (SS) and salt restriction (SR) strategies, respectively, were followed for 1 year. Salt substitute users were further divided by potassium chloride (KCl) content (13% vs 25%) and duration (9-11 vs 12 months). The 24-h eUNaE and estimated urinary potassium excretion (eUKE) levels were calculated using the Kawasaki formula from spot urine sample. The SS group ( Conclusion: Compared with salt restriction, salt substitute results in more sodium reduction and greater potassium increase. In spite of this, it does not result in better control of blood pressure, especially for the group receiving 13% KCl.

Indexed as

Chinacohortreal-worldsalt restrictionsalt substitute

Identifiers

PMID39744240
PMCPMC11688233

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.