Evidence map›Paper›PMID 39744230›Full record

ArticleTheranostics2025

Tumor immunomodulation by nanoparticle and focused ultrasound alters gut microbiome in a sexually dimorphic manner.

Akansha Singh, Sri Vidhya Chandrasekar, Vishnu Thayil Valappil, Joy Scaria, Ashish Ranjan

Abstract read
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Akansha SinghDepartment of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX 75390, USA.
Sri Vidhya ChandrasekarDepartment of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX 75390, USA.
Vishnu Thayil ValappilDepartment of Veterinary Pathobiology, Oklahoma State University, Stillwater, OK 74078, USA.
Joy ScariaDepartment of Veterinary Pathobiology, Oklahoma State University, Stillwater, OK 74078, USA.
Ashish RanjanDepartment of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX 75390, USA.

Funding

Novel focused ultrasound enhanced calreticulin-nanoparticle for immune primed melanoma immunotherapyR37CA239150 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI RANJAN, ASHISH · 2019 to 2025
$2.9M
Role of histotripsy synergized CD40 signaling in the re-engineering of cold tumorsR01CA260974 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI Ashish Ranjan · 2022 to 2026
$2.0M
NCI NIH HHS R01 CA260974NCI NIH HHS R01 CA284741NCI NIH HHS R37 CA239150
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gastrointestinal MicrobiomeImmunomodulationNanoparticlesAnimalsCalreticulinCell Line, TumorCytokinesFemaleImmunogenic Cell DeathMaleMiceMice, Inbred C57BLMouth NeoplasmsSex CharacteristicsCalreticulinCytokinesFocused UltrasoundGut MicrobiomeImmunomodulationNanoparticleSexual dimorphism

Identifiers

PMID39744230
PMCPMC11667224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.