Evidence map›Paper›PMID 39744227›Full record

Trial reportTheranostics2025

Optical molecular imaging in oral- and oropharyngeal squamous cell carcinoma using a novel uPAR-targeting near-infrared imaging agent FG001 (ICG-Glu-Glu-AE105): An explorative phase II clinical trial.

Amanda Oester Andersen, Anders Christensen, Karina Straede, Mads Lawaetz, Christoffer Holst Hahn, Nicklas Rubek, Irene Wessel, Giedrius Lelkaitis, Katalin Kiss, Natasja Paaske and 3 more

Abstract readClinical Trial, Phase II
In one paragraph

Trial report in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Amanda Oester AndersenDepartment of Otorhinolaryngology, Head & Neck Surgery and Audiology, Copenhagen University Hospital, Rigshospitalet, Denmark.
Anders ChristensenDepartment of Otorhinolaryngology, Head & Neck Surgery and Audiology, Copenhagen University Hospital, Rigshospitalet, Denmark.
Karina StraedeDepartment of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging (CMI), Copenhagen University Hospital, Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, Denmark.
Mads LawaetzDepartment of Otorhinolaryngology, Head & Neck Surgery and Audiology, Copenhagen University Hospital, Rigshospitalet, Denmark.
Christoffer Holst HahnDepartment of Otorhinolaryngology, Head & Neck Surgery and Audiology, Copenhagen University Hospital, Rigshospitalet, Denmark.
Nicklas RubekDepartment of Otorhinolaryngology, Head & Neck Surgery and Audiology, Copenhagen University Hospital, Rigshospitalet, Denmark.
Irene WesselDepartment of Otorhinolaryngology, Head & Neck Surgery and Audiology, Copenhagen University Hospital, Rigshospitalet, Denmark.
Giedrius LelkaitisDepartment of Pathology, Copenhagen University Hospital, Rigshospitalet, Denmark.
Katalin KissDepartment of Pathology, Copenhagen University Hospital, Rigshospitalet, Denmark.
Natasja PaaskeDepartment of Otorhinolaryngology, Head & Neck Surgery and Audiology, Copenhagen University Hospital, Rigshospitalet, Denmark.
Anne PoulsenFluoGuide A/S, Copenhagen, Denmark.
Christian von BuchwaldDepartment of Otorhinolaryngology, Head & Neck Surgery and Audiology, Copenhagen University Hospital, Rigshospitalet, Denmark.
Andreas KjaerDepartment of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging (CMI), Copenhagen University Hospital, Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Molecular ImagingMouth NeoplasmsOptical ImagingOropharyngeal NeoplasmsAdultAgedCarcinoma, Squamous CellFemaleHumansIndocyanine GreenMaleMiddle AgedProspective StudiesReceptors, Urokinase Plasminogen ActivatorSpectroscopy, Near-InfraredSquamous Cell Carcinoma of Head and NeckIndocyanine GreenReceptors, Urokinase Plasminogen Activatorfluorescence-guided surgeryhead and neck cancernear-infraredoptical imaginguPAR

Identifiers

PMID39744227
PMCPMC11667226

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.