Evidence map›Paper›PMID 39744209›Full record

ArticleFrontiers in cardiovascular medicine2024

The association between blood metals and cardiovascular diseases: findings from National Health and Nutrition Examination Survey 2011-2020.

Bin Li, Haiyue Liu, Devrakshita Mishra, Zhen Yuan, Yizhi Zhang, Longzhen Zhang, Yanshu Huang, Ye Zhang, Ju Lin, Jianyou Chen and 1 more

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. An Exploration of Machine Learning Methods in Human Biomonitoring.International journal of environmental research and public health · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bin Li *Department of Cardiology, Xiamen Chang Gung Hospital, School of Medicine, Huaqiao University, Xiamen, China.
Haiyue Liu *Xiamen Key Laboratory of Genetic Testing, Department of Laboratory Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Devrakshita MishraDepartment of Clinical Medicine, School of Medicine, Xiamen University, Xiamen, China.
Zhen YuanDepartment of Cardiology, Xiamen Chang Gung Hospital, School of Medicine, Huaqiao University, Xiamen, China.
Yizhi ZhangDepartment of Cardiology, Xiamen Chang Gung Hospital, School of Medicine, Huaqiao University, Xiamen, China.
Longzhen ZhangDepartment of Cardiology, Xiamen Chang Gung Hospital, School of Medicine, Huaqiao University, Xiamen, China.
Yanshu HuangDepartment of Cardiology, Xiamen Chang Gung Hospital, School of Medicine, Huaqiao University, Xiamen, China.
Ye ZhangDepartment of Cardiology, Xiamen Chang Gung Hospital, School of Medicine, Huaqiao University, Xiamen, China.
Ju LinDepartment of Cardiology, Xiamen Chang Gung Hospital, School of Medicine, Huaqiao University, Xiamen, China.
Jianyou ChenDepartment of Cardiology, Xiamen Chang Gung Hospital, School of Medicine, Huaqiao University, Xiamen, China.
Zuheng LiuDepartment of Cardiology, Xiamen Key Laboratory of Cardiac Electrophysiology, Xiamen Institute of Cardiovascular Diseases, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Previous studies have examined the relationship between cardiovascular diseases (CVDs) and blood metal levels. However, fewer studies have investigated the role of the combinations of blood metals on CVDs. In the current study, our aim is to explore the roles of specific blood metals and further develop a model to differentiate between healthy participants and CVD patients using database from the National Health and Nutrition Examination Survey (NHANES). Methods: Data from the National Health and Nutrition Examination Survey (NHANES) from 2011 to 2020 were collected and utilized in the present study. Demographic characteristics and examination results were gathered and analyzed to compare CVD and non-CVD participants. Logistic regression and random forest analyses were employed to determine the odds ratios and the effects of various blood metals on CVDs. Results: A total of 23,448 participants were included and analyzed. Participants were divided into CVD ( Conclusions: In summary, blood metals may play an important role in the onset and progression of CVDs, and they can be used to develop a predictive model for CVDs, which might be beneficial for the identification and early diagnosis of CVDs.

Indexed as

blood metalscadmiumcardiovascular diseasesleadNHANES

Identifiers

PMID39744209
PMCPMC11688349

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.