Evidence map›Paper›PMID 39744127›Full record

ArticleFrontiers in pharmacology2024

Polysaccharides derived from golden mushroom (

Yamina Alioui, Hidayat Ullah, Sharafat Ali, Mujeeb Ur Rahman, Maroua Elkharti, Nabeel Ahmed Farooqui, Ata Ur Rehman, Muhammad Ilyas, Duaa M Alsholi, Nimra Zafar Siddiqi and 3 more

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Frontiers in immunology · 2026
    Article
  3. Frontiers in pharmacology · 2026
    Article
  4. Frontiers in nutrition · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. International journal of molecular sciences · 2025
    Article
  9. Frontiers in nutrition · 2025
    Article
  10. Review
  11. Frontiers in pharmacology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yamina AliouiDepartment of Biotechnology, College of Basic Medical Science, Dalian Medical University, Dalian, China.
Hidayat UllahDepartment of Biotechnology, College of Basic Medical Science, Dalian Medical University, Dalian, China.
Sharafat AliDepartment of Biochemistry and Molecular Biology, College of Basic Medical Science, Dalian Medical University, Dalian, China.
Mujeeb Ur RahmanDepartment of Biotechnology, College of Basic Medical Science, Dalian Medical University, Dalian, China.
Maroua ElkhartiDepartment of Biochemistry and Molecular Biology, College of Basic Medical Science, Dalian Medical University, Dalian, China.
Nabeel Ahmed FarooquiDepartment of Biotechnology, College of Basic Medical Science, Dalian Medical University, Dalian, China.
Ata Ur RehmanMultidisciplinary Neuroprotection Laboratories, Duke University School of Medicine, Durham, NC, United States.
Muhammad IlyasDepartment of Biotechnology, College of Basic Medical Science, Dalian Medical University, Dalian, China.
Duaa M AlsholiDepartment of Medical Laboratories Sciences, Faculty of Allied Medical Sciences, Zarqa University, Zarqa, Jordan.
Nimra Zafar SiddiqiDepartment of Biotechnology, College of Basic Medical Science, Dalian Medical University, Dalian, China.
Muhsin AliDepartment of Biotechnology, College of Basic Medical Science, Dalian Medical University, Dalian, China.
Liang WangStem Cell Clinical Research Center, National Joint Engineering Laboratory, Regenerative Medicine Center, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Yi XinDepartment of Biotechnology, College of Basic Medical Science, Dalian Medical University, Dalian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Inflammatory bowel disease (IBD), including ulcerative colitis, is marked by intestinal barrier disruptions, immune system dysregulation, and an imbalance in the gut microbiota. The golden chanterelle mushroom, Methods: To induce colitis BALB/c mice were provided to consume autoclaved water with 3% DSS for 7 days, followed by 14 days of CCP supplementation. To assess the effects of CCP, histological analysis of colon tissue was performed, gene expression, inflammatory responses, tight junction proteins expression, gut barrier integrity, and cytokines levels were measured and analyzed and 16S rRNA sequencing were evaluated. Results and Discussion: CCP treatment alleviates colitis symptoms by improving body weight, and enhancing intestinal integrity through increased mucin-2 and tight junction protein expression. Additionally, CCP administration regulates the altered immune response by mitigating the expression of pro-inflammatory cytokines and upregulating anti-inflammatory cytokines. Furthermore, CCP supplementation effectively modulates DSS-induced dysbiosis as demonstrated by 16S rRNA sequencing results. These findings suggest that crude polysaccharides from the golden chanterelle mushroom,

Indexed as

Cantharellus cibarius Fr.dextran sulfate sodiumgut microbiotainflammatory bowel diseaseintestinal barrierpolysaccharides

Identifiers

PMID39744127
PMCPMC11688367

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.