ArticleFrontiers in neurology2024
Day 3 neutrophil-to-lymphocyte ratio and its derived indices predict 90-day poor outcomes following mechanical thrombectomy in acute ischemic stroke patients.
Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed.
- Neutrophil-Monocyte-to-Lymphocyte Ratio as a Valid Prognostic Tool for Acute Ischemic Stroke With Performance Comparable to Neutrophil-to-Lymphocyte Ratio.Brain and behavior · 2026Article
- The Association of the Neutrophil-to-Lymphocyte Ratio and the D-dimer-to-Albumin Ratio with Deep Vein Thrombosis in Patients with Spontaneous Intracerebral Hemorrhage.International journal of general medicine · 2026Article
- Sequential NIHSS-NLR monitoring after endovascular thrombectomy: malignant cerebral oedema and inflammatory futility in a two-phase derivation study.Frontiers in neurology · 2026Article
- Development of the Neutrophil-to-Platelet Ratio (NPR) Integrated with Machine Learning for Predicting Early Mortality After Mechanical Thrombectomy in Acute Ischemic Stroke.Journal of inflammation research · 2026Article
- Distinct trajectory patterns of neutrophil-to-albumin ratio predict clinical outcomes after endovascular therapy in large vessel occlusion stroke.Frontiers in aging neuroscience · 2025Article
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8 authors.
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Abstract
Objective: To investigate the dynamic changes in neutrophil-to-lymphocyte ratio (NLR) and its derived indices following mechanical thrombectomy (MT) in patients with acute ischemic stroke (AIS) and evaluate their predictive value for prognosis. Methods: This single-center retrospective cohort study included AIS patients who underwent MT at Zhongshan Hospital of Xiamen University from January 2018 to February 2024. Peripheral blood samples were collected on admission, day 1, and day 3 after MT to determine the NLR, derived NLR (dNLR), and neutrophil-monocyte-to-lymphocyte ratio (NMLR). The primary endpoint was poor functional outcome at 90 days (modified Rankin scale score 3-6). The secondary endpoints included post-operative hemorrhagic transformation, malignant cerebral edema, in-hospital mortality, and 90-day all-cause mortality. Receiver operating characteristic (ROC) curve analysis was used to evaluate predictive performance, and multivariate logistic regression models were employed to explore the independent associations between inflammatory markers and prognosis. Results: A total of 423 eligible patients were included. Both groups showed similar dynamic trends in inflammatory markers, peaking on day 1 post-MT and subsequently declining. However, the poor outcome group ( Conclusion: Inflammatory markers (NLR, dNLR, and NMLR) on day 3 post-MT can serve as independent predictors of prognosis in AIS patients treated with MT. Dynamic monitoring of inflammatory markers may facilitate early risk stratification and guide individualized treatment strategies.
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