Evidence map›Paper›PMID 39744095›Full record

ArticlemLife2024

Genotype-microbiome-metabolome associations in early childhood and their link to BMI.

Andrea Aparicio, Zheng Sun, Diane R Gold, Jessica A Lasky-Su, Augusto A Litonjua, Scott T Weiss, Kathleen Lee-Sarwar, Yang-Yu Liu

Abstract read
In one paragraph

Article in mLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Andrea AparicioDepartment of Medicine, Brigham and Women's Hospital and Harvard Medical School Channing Division of Network Medicine Boston Massachusetts USA.ORCID 0000-0001-7195-8273
Zheng SunDepartment of Medicine, Brigham and Women's Hospital and Harvard Medical School Channing Division of Network Medicine Boston Massachusetts USA.
Diane R GoldDepartment of Medicine, Brigham and Women's Hospital and Harvard Medical School Channing Division of Network Medicine Boston Massachusetts USA.
Jessica A Lasky-SuDepartment of Medicine, Brigham and Women's Hospital and Harvard Medical School Channing Division of Network Medicine Boston Massachusetts USA.
Augusto A LitonjuaDivision of Pediatric Pulmonary Medicine, Golisano Children's Hospital at Strong University of Rochester Medical Center Rochester New York USA.
Scott T WeissDepartment of Medicine, Brigham and Women's Hospital and Harvard Medical School Channing Division of Network Medicine Boston Massachusetts USA.
Kathleen Lee-SarwarDepartment of Medicine, Brigham and Women's Hospital and Harvard Medical School Channing Division of Network Medicine Boston Massachusetts USA.
Yang-Yu LiuDepartment of Medicine, Brigham and Women's Hospital and Harvard Medical School Channing Division of Network Medicine Boston Massachusetts USA.ORCID https://orcid.org/0000-0003-2728-4907

Funding

VISUAL INDICES OF NEUROTOXICITYP30ES001247 · NIEHS · UNIVERSITY OF ROCHESTER · PI Martha Susiarjo · 1985 to 2026
$42.8M
Multi-omic approaches to mechanisms of vitamin D, environmental influences, and the microbiome on asthmaUH3OD023268 · OD · BRIGHAM AND WOMEN'S HOSPITAL · PI LITONJUA, AUGUSTO A, WEISS, SCOTT T · 2018 to 2022
$13.5M
Randomized Trial: Maternal Vitamin D Supplementation to Prevent Childhood AsthmaU01HL091528 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LITONJUA, AUGUSTO A, WEISS, SCOTT T · 2009 to 2013
$10.0M
Mechanistic insights into asthma pathogenesis through the integration of asthma genes, risk exposures, and metabolomicsR01HL141826 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LASKY-SU, JESSICA A · 2018 to 2021
$3.4M
Multi-omic approaches to mechanisms of vitamin D, environmental influences, and the microbiome on asthmaUG3OD023268 · OD · BRIGHAM AND WOMEN'S HOSPITAL · PI LITONJUA, AUGUSTO A, WEISS, SCOTT T · 2016 to 2017
$2.8M
VDAART FLORA ANCILLARY STUDYR01HL108818 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLD, DIANE R · 2011 to 2013
$1.3M
Multi-Omics Analysis of the Association of Polyunsaturated Fatty Acids with Asthma and Allergy in ChildhoodK08HL148178 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LEE-SARWAR, KATHLEEN A · 2019 to 2022
$683k
NHLBI NIH HHS K08 HL148178NHLBI NIH HHS R01 HL108818NHLBI NIH HHS R01 HL141826NHLBI NIH HHS U01 HL091528NIEHS NIH HHS P30 ES001247NIH HHS UG3 OD023268NIH HHS UH3 OD023268
6 · The paper itself

Abstract

Through the analysis of data from children aged 6 months to 8 years enrolled in the Vitamin D Antenatal Asthma Reduction Trial (VDAART), significant simultaneous associations were identified between variants in the fragile histidine triad (

Identifiers

PMID39744095
PMCPMC11685832

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.