Evidence map›Paper›PMID 39744072›Full record

ArticleBJUI compass2024

Prospective per-target analysis of the added value of the PrecisionPoint Transperineal Access System in cognitive prostate biopsy of MRI targets.

Luca Orecchia, Stefano Germani, Gaia Colalillo, Angelica Fasano, Matteo Ricci, Eleonora Rosato, Anastasios D Asimakopoulos, Simone Albisinni, Enrico Finazzi Agrò, Guglielmo Manenti and 1 more

Abstract read
In one paragraph

Article in BJUI compass, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Luca OrecchiaUrology Unit AOU Policlinico Tor Vergata University Hospital Rome Italy.ORCID https://orcid.org/0000-0001-8376-5380
Stefano GermaniUrology Unit AOU Policlinico Tor Vergata University Hospital Rome Italy.
Gaia ColalilloUrology Unit AOU Policlinico Tor Vergata University Hospital Rome Italy.ORCID https://orcid.org/0000-0001-8703-5975
Angelica FasanoUrology Unit AOU Policlinico Tor Vergata University Hospital Rome Italy.
Matteo RicciUrology Unit AOU Policlinico Tor Vergata University Hospital Rome Italy.
Eleonora RosatoUrology Unit AOU Policlinico Tor Vergata University Hospital Rome Italy.
Anastasios D AsimakopoulosUrology Unit AOU Policlinico Tor Vergata University Hospital Rome Italy.ORCID https://orcid.org/0000-0002-7230-579X
Simone AlbisinniUrology Unit AOU Policlinico Tor Vergata University Hospital Rome Italy.ORCID https://orcid.org/0000-0001-5529-3064
Enrico Finazzi AgròUrology Unit AOU Policlinico Tor Vergata University Hospital Rome Italy.
Guglielmo ManentiDepartment of Diagnostic and Interventional Radiology, Molecular Imaging and Radiotherapy, AOU Policlinico Tor Vergata University of Rome Tor Vergata Rome Italy.
Roberto MianoUrology Unit AOU Policlinico Tor Vergata University Hospital Rome Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The objective of this study is to evaluate the diagnostic performance of perineal access cannulas tethered to a biplanar ultrasound probe in cognitive transperineal prostate biopsies of targets identified by multiparametric magnetic resonance imaging (mpMRI) by comparing the results of the PrecisionPoint (PP) Transperineal Access System with the double-freehand (DFH) technique. Patients and methods: All patients who underwent cognitive transperineal prostate biopsy of mpMRI targets using the PP or DFH technique between November 2020 and September 2023 were enrolled. All data related to mpMRI target biopsies were stratified by technique, visibility in transrectal ultrasound and analysed by comparing PP versus DFH. A standardised anaesthesia protocol with 1% mepivacaine was used in all biopsies. The tolerability of the procedures was assessed using a visual analogue scale (VAS). Results: The number of mpMRI targets sampled was 166 in PP and 242 in DFH. In target biopsies, the PP system was associated with better diagnostic performance for clinically significant prostate cancer (Gleason score ≥3 + 4) compared to DFH for both ultrasound-visible targets (61.4% vs. 48.0%) and non-visible targets (41.4% vs. 14.9%) ( Conclusion: The PrecisionPoint Transperineal Access System enabled more precise and higher quality biopsies, resulting in improved histological characterisation of prostate cancer compared to the DFH approach. The use of a perineal cannula did not increase the pain perceived by patients and also required less local anaesthetic during the biopsy.

Indexed as

cognitive biopsylocal anaesthesiaPrecisionPointprostate biopsyprostate biopsy complicationsprostate cancerprostate MRItransperineal biopsy

Identifiers

PMID39744072
PMCPMC11685168

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.