Evidence map›Paper›PMID 39743938›Full record

ReviewTurkish journal of ophthalmology2024

The Role of In Vivo Confocal Microscopy in Ocular Allergies.

Cem Şimşek, Takashi Kojima, Murat Doğru

Abstract readReview
In one paragraph

Review in Turkish journal of ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Cem ŞimşekMuğla Sıtkı Koçman University Faculty of Medicine, Department of Ophthalmology, Muğla, Türkiye.ORCID 0000-0001-8003-745X
Takashi KojimaKeio University Faculty of Medicine, Department of Ophthalmology, Tokyo, Japan.ORCID 0000-0002-5016-0155
Murat DoğruKeio University Faculty of Medicine, Department of Ophthalmology, Tokyo, Japan.ORCID 0000-0003-1487-2435

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In vivo confocal microscopy (IVCM) is a non-invasive imaging technique used to visualize the layers of the cornea and conjunctiva in real time. In patients with atopic keratoconjunctivitis (AKC) and vernal keratoconjunctivitis (VKC), this technology can be useful in diagnosing and monitoring the disease, as well as evaluating the efficacy of treatments. IVCM can reveal subclinical abnormalities in the corneal and conjunctival epithelium such as inflammatory cell infiltrates and tissue damage, which can provide insight into the pathogenesis of AKC. In AKC, IVCM reveals changes around the conjunctival papillae, inflammatory cells around punctate defects in the corneal epithelium, changes in subbasal nerve morphology, and deteriorations in the goblet cells in the meibomian gland are observed. In VKC, alterations can be observed in the diameter, brightness and nucleus/cytoplasm ratio of the superficial epithelial cells in the cornea. The use of IVCM in AKC and VKC can therefore aid in the early detection and management of the disease, as well as contribute to a better understanding of its underlying mechanisms.

Indexed as

ConjunctivaConjunctivitis, AllergicMicroscopy, ConfocalCorneaHumansKeratoconjunctivitisAtopic keratoconjunctivitisconjunctivacorneain vivo confocal microscopymeibomian glandsvernal keratoconjunctivitis

Identifiers

PMID39743938
PMCPMC11707458

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.