Evidence map›Paper›PMID 39743810›Full record

ReviewJournal of complementary & integrative medicine2025

Apitherapy for diabetes mellitus: mechanisms and clinical implications.

Andrés Jagua-Gualdrón, Nicolai Andrés García-Reyes, Roger Edwin Fernández-Bernal

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of complementary & integrative medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Andrés Jagua-GualdrónNational University of Colombia, Bogota, Colombia.
Nicolai Andrés García-ReyesNational University of Colombia, Bogota, Colombia.
Roger Edwin Fernández-BernalInternational College of Apitherapy, Bogota, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDiabetes mellitus is a complex disease in terms of its causes and pathophysiological processes, it produces a significant impact on health and leads to complications that are difficult to manage. CONTENT: This review summarizes and analyzes recent advances in the understanding of the mechanisms of diabetes mellitus and how apitherapy affects them. Also present the available clinical evidence on its application. SUMMARY: Apitherapy (complementary-integral use of beehive products) is a potentially useful therapeutic system with a significant level of evidence. This review shows and analyzes the preclinical and clinical evidence on the use of apitherapy in diabetes mellitus. OUTLOOK: Apitherapy shows significant effects on epigenetics, chronic inflammation, oxidative stress, metabolic control, dysbiosis, premature cell death and tissue remodeling. Clinical evidence shows an impact on these mechanisms. Apitherapy is a very useful complementary medicine in the treatment of diabetes mellitus.

Indexed as

Complementary TherapiesDiabetes MellitusAnimalsEpigenesis, GeneticHumansOxidative Stressapitherapybee venomsdiabetes mellituspropolisroyal jelly

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.