Evidence map›Paper›PMID 39743620›Full record

ArticleEye and vision (London, England)2025

Comparison of the inverted internal limiting membrane flap technique without versus with an autologous blood clot for treating macular hole-associated retinal detachment.

Ke Zhu, Yingchao Wang, Boya Lei, Ling Chen, Yanqiong Zhang, Qing Chang, Gezhi Xu, Yingqin Ni

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Eye and vision (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. OVD-assisted press injection in gasless surgery for sectorial inverted internal limiting membrane flap stabilization.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ke ZhuEye Institute and Department of Ophthalmology, Eye and Ear Nose, Throat Hospital of Fudan University, 83 Fen Yang Road, Shanghai, 200031, China.
Yingchao WangEye Institute and Department of Ophthalmology, Eye and Ear Nose, Throat Hospital of Fudan University, 83 Fen Yang Road, Shanghai, 200031, China.
Boya LeiEye Institute and Department of Ophthalmology, Eye and Ear Nose, Throat Hospital of Fudan University, 83 Fen Yang Road, Shanghai, 200031, China.
Ling ChenEye Institute and Department of Ophthalmology, Eye and Ear Nose, Throat Hospital of Fudan University, 83 Fen Yang Road, Shanghai, 200031, China.
Yanqiong ZhangEye Institute and Department of Ophthalmology, Eye and Ear Nose, Throat Hospital of Fudan University, 83 Fen Yang Road, Shanghai, 200031, China.
Qing ChangEye Institute and Department of Ophthalmology, Eye and Ear Nose, Throat Hospital of Fudan University, 83 Fen Yang Road, Shanghai, 200031, China.
Gezhi XuEye Institute and Department of Ophthalmology, Eye and Ear Nose, Throat Hospital of Fudan University, 83 Fen Yang Road, Shanghai, 200031, China. drxugezhieent@126.com.
Yingqin NiEye Institute and Department of Ophthalmology, Eye and Ear Nose, Throat Hospital of Fudan University, 83 Fen Yang Road, Shanghai, 200031, China. yingqinnieent@163.com.ORCID http://orcid.org/0009-0007-3231-0918

Funding

Shanghai "Rising Stars of Medical Talents" Youth Development Program SHWSRS(2023)_62Shanghai Sailing Program 20YF1404800Specialized Clinical Research Program of Shanghai Municipal Health Commission 20235Y0027Youth Project of the National Natural Science Fund 82000918Youth Project of the National Natural Science Fund 82101124
6 · The paper itself

Abstract

backgroundTo investigate the anatomical and functional outcomes of macular hole-associated retinal detachment (MHRD) after vitrectomy using the inverted internal limiting membrane (ILM) flap technique with autologous blood clot (ABC).

methodsThis retrospective observational study included 80 eyes with MHRD that underwent vitrectomy with ILM flap without (46 eyes) or with ABC (34 eyes). Fundus photography and optical coherence tomography were evaluated. The pre- and postoperative best-corrected visual acuities (BCVAs) and BCVA improvement were compared between the two groups.

resultsThe MH closure rates after initial surgery were similar in the ILM flap group and ILM flap with ABC group [40 (87%) vs. 29 (85%) eyes, respectively]. The proportion of eyes with hyperreflective bridging tissue (HBT) was lower in the ILM flap group than ILM flap with ABC group [13 (32%) vs. 16 (55%) eyes, P = 0.060]. The postoperative improvement in BCVA was significantly better in the ILM flap group (P = 0.027). Multiple linear regression analysis revealed that preoperative BCVA was positively associated with postoperative improvement in BCVA (β = 0.638, P = 0.000), while the ILM flap with ABC technique was negatively associated with postoperative improvement in BCVA (β =  - 0.299, P = 0.039, adjusted r

conclusionsThe inverted ILM flap technique alone resulted in better foveal configurations and visual outcomes than the ILM flap technique combined with ABC in patients with MHRD.

Indexed as

Autologous blood clotBest-corrected visual acuityInternal limiting membrane flap techniqueMacular hole-associated retinal detachmentMacular hole closure

Identifiers

PMID39743620
PMCPMC11694389

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.