Evidence map›Paper›PMID 39743615›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2025

Assessment of fully quantitative and simplified methods for analysis of [

Xavier Palard-Novello, Rutger B Henrar, Daniela E Oprea-Lager, Matthijs C F Cysouw, Patrick Schober, Lioe-Fee de Geus-Oei, Alexander L Vahrmeijer, Harry Hendrikse, Geert Kazemier, Marijke den Hollander and 5 more

Abstract read
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In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Repeatability of semi-quantitative [European journal of nuclear medicine and molecular imaging · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xavier Palard-Novello *Univ Rennes, CLCC Eugène Marquis, INSERM, LTSI - UMR 1099, Rennes, France. x.palard@rennes.unicancer.fr.
Rutger B Henrar *Amsterdam UMC location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.
Daniela E Oprea-LagerAmsterdam UMC location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.
Matthijs C F CysouwAmsterdam UMC location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.
Patrick SchoberAmsterdam UMC location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.
Lioe-Fee de Geus-OeiLeiden University Medical Center, Albinusdreef 2, Leiden, the Netherlands.
Alexander L VahrmeijerLeiden University Medical Center, Albinusdreef 2, Leiden, the Netherlands.
Harry HendrikseAmsterdam UMC location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.
Geert KazemierAmsterdam UMC location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.
Marijke den HollanderAmsterdam UMC location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.
Robert C SchuitAmsterdam UMC location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.
Albert D WindhorstAmsterdam UMC location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.
Ronald BoellaardAmsterdam UMC location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.
Rutger-Jan Swijnenburg *Amsterdam UMC location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.
Maqsood Yaqub *Amsterdam UMC location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.

Funding

Cancer Center Amsterdam 2021-2-29Cholangiocarcinoma Foundation Cholangiocarcinoma FoundationKWF Kankerbestrijding 11289
6 · The paper itself

Abstract

purposeThe aim of this study was to validate simplified methods for quantifying [

methodsTen patients with pancreatobiliary cancer underwent a 90-min dynamic PET/CT scan using a long axial field of view system. Arterial blood samples were used to establish calibrated plasma-input function from both continuous arterial sampling and image-derived input function (IDIF). Lesional [

resultsOne patient was excluded due to discontinued scan acquisition and missing arterial sampling. Thirteen tumoral lesions and 11 non-tumoral lesions were included. A reversible 2-tissue-compartment model showed most preferrable fits for all types of [

conclusionImage-based TBR and SUVmean at 60-70 min p.i are suitable for quantifying [

trial registrationEudraCT, EudraCT 2022-001867-29. Registered 02 November 2022.

Indexed as

Biliary Tract NeoplasmsPancreatic NeoplasmsPositron Emission Tomography Computed TomographyAgedAged, 80 and overBiological TransportFemaleGallium RadioisotopesHumansMaleMiddle AgedQuinolines68Ga-FAPIGallium RadioisotopesQuinolines[68Ga]Ga-FAPI-46LAFOV PET/CTPancreatobiliary cancerPharmacokineticsQuantification

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.