ArticleNature2025
Aspartate signalling drives lung metastasis via alternative translation.
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Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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37citing papers in PubMed
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Who cites it
37 citing papers in PubMed.
- Metal-phenolic nanocapsules enable a self-amplifying cuproptosis-STING cascade for synergistic cancer immunotherapy.Bioactive materials · 2026Article
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- Orchestrating the metastatic symphony: the role of extracellular vesicles in the epithelial-mesenchymal transition and pulmonary niche formation of breast cancer.Biological reviews of the Cambridge Philosophical Society · 2026Review
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- Metabolites and cancer metastasis.Oncogene · 2026Review
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- A high-resolution circulating metabolic atlas of lung adenocarcinoma progression supports early and accurate diagnosis.Cell reports. Medicine · 2026Article
- Post-translational modifications in metabolic reprogramming: implications for metabolic therapy and immunotherapy in cancer.Signal transduction and targeted therapy · 2026Review
- Amplification of Endoplasmic Reticulum Stress via Inhibiting Lipid Droplet Formation to Enhance Chemodynamic Immunotherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Article
- Targeting the Lipid Metabolism Proteins FASN and GPAM in Alveolar Type II Cells Decreases Lung Metastasis.Cancer discovery · 2026Article
- Aspartate deficiency amplifies cGAS-STING signaling in antitumor immunity.The Journal of clinical investigation · 2026Article
- Amino Acids as Targets for Immunotherapy against Solid Tumors.Cell biochemistry and biophysics · 2026Review
- The advent of precision nutrigeroscience in cancer: from clinic towards molecular biology.Journal of advanced research · 2026Review
- Targeting SCAMP2 by a natural product auxarconjugatin B for glioblastoma therapyActa pharmaceutica Sinica. B · 2026Article
- Reprogramming of nitrogen metabolism in tumors: mechanisms and therapeutic implications.Amino acids · 2026Review
- Arginine dependency in omental metastasis of epithelial ovarian cancer reveals a therapeutic vulnerability.Cell death & disease · 2026Article
- The 2025 lung cancer landscape: advances in screening, molecular taxonomy and therapeutic strategy: a narrative review.Translational lung cancer research · 2026Review
- The pre-metastatic niche: mechanisms, heterogeneity, and therapeutic opportunities.Molecular cancer · 2026Review
- A shift in the cellular redox state redirects aspartate for export under glucose deprivation.Cancer & metabolism · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
37 authors.
Ginevra DoglioniLaboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, VIB, Leuven, Belgium.ORCID http://orcid.org/0000-0002-9470-4476
Juan Fernández-García *Laboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, VIB, Leuven, Belgium.ORCID http://orcid.org/0000-0003-3422-3627
Sebastian Igelmann *Laboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, VIB, Leuven, Belgium.ORCID http://orcid.org/0000-0001-6133-4184
Patricia Altea-Manzano *Laboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, VIB, Leuven, Belgium.ORCID http://orcid.org/0000-0002-7075-2051
Arnaud BlommeLaboratory of Cancer Signaling, GIGA-Institute, University of Liège, Liège, Belgium.ORCID http://orcid.org/0000-0003-4183-8726
Rita La RovereLaboratory of Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
Xiao-Zheng LiuLaboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, VIB, Leuven, Belgium.ORCID http://orcid.org/0000-0002-8452-6848
Yawen LiuLaboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, VIB, Leuven, Belgium.
Tine TricotLaboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, VIB, Leuven, Belgium.ORCID http://orcid.org/0000-0002-6710-4838
Max NobisLaboratory of Intravital Microscopy and Dynamics of Tumor Progression, VIB Center for Cancer Biology, VIB, Leuven, Belgium.ORCID http://orcid.org/0000-0002-1861-1390
Ning AnLaboratory of Cancer Signaling, GIGA-Institute, University of Liège, Liège, Belgium.ORCID http://orcid.org/0000-0001-9512-6869
Marine LeclercqLaboratory of Cancer Signaling, GIGA-Institute, University of Liège, Liège, Belgium.ORCID http://orcid.org/0000-0002-3974-0060
Sarah El KharrazLaboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, VIB, Leuven, Belgium.
Panagiotis KarrasLaboratory for Molecular Cancer Biology, VIB Center for Cancer Biology, VIB, Leuven, Belgium.ORCID http://orcid.org/0000-0002-7642-0875
Yu-Heng HsiehLeibniz Institut für Analytische Wissenschaften-ISAS-e.V., Dortmund, Germany.
Fiorella A SolariLeibniz Institut für Analytische Wissenschaften-ISAS-e.V., Dortmund, Germany.
Luiza Martins Nascentes MeloDepartment of Dermatology, University Hospital Essen and German Cancer Consortium, Essen, Germany.ORCID http://orcid.org/0000-0002-5980-5220
Gabrielle AlliesDepartment of Dermatology, University Hospital Essen and German Cancer Consortium, Essen, Germany.
Annalisa ScopellitiLaboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, VIB, Leuven, Belgium.
Matteo RossiLaboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, VIB, Leuven, Belgium.ORCID http://orcid.org/0000-0002-1206-1244
Ines VermeireLaboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, VIB, Leuven, Belgium.ORCID http://orcid.org/0000-0003-3366-7410
Dorien BroekaertLaboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, VIB, Leuven, Belgium.ORCID http://orcid.org/0000-0002-9777-1607
Ana Margarida Ferreira CamposLaboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, VIB, Leuven, Belgium.ORCID http://orcid.org/0000-0002-8832-7686
Patrick NevenDepartment of Gynaecology and Obstetrics, UZ Leuven, Leuven, Belgium.
Marion MaetensLaboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.
Karen Van BaelenDepartment of Gynaecology and Obstetrics, UZ Leuven, Leuven, Belgium.
H Furkan AlkanLaboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, VIB, Leuven, Belgium.ORCID http://orcid.org/0000-0003-0078-248X
Mélanie PlanqueLaboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, VIB, Leuven, Belgium.
Giuseppe FlorisDepartment of Pathology, UZ Leuven, Leuven, Belgium.
Albert SickmannLeibniz Institut für Analytische Wissenschaften-ISAS-e.V., Dortmund, Germany.
Alpaslan TasdoganDepartment of Dermatology, University Hospital Essen and German Cancer Consortium, Essen, Germany.ORCID http://orcid.org/0000-0003-2543-852X
Jean-Christophe MarineLaboratory for Molecular Cancer Biology, VIB Center for Cancer Biology, VIB, Leuven, Belgium.ORCID http://orcid.org/0000-0003-2433-9837
Colinda L G J ScheeleLaboratory of Intravital Microscopy and Dynamics of Tumor Progression, VIB Center for Cancer Biology, VIB, Leuven, Belgium.ORCID http://orcid.org/0000-0001-8999-5451
Christine DesmedtLaboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-5223-5579
Geert BultynckLaboratory of Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-5968-4828
Pierre CloseLaboratory of Cancer Signaling, GIGA-Institute, University of Liège, Liège, Belgium.
Sarah-Maria FendtLaboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, VIB, Leuven, Belgium. sarah-maria.fendt@kuleuven.be.ORCID http://orcid.org/0000-0001-6018-9296
Funding
King Baudouin Foundation and H.F.AKU LeuvenUniversity Hospitals from Leuven
Abstract
Lung metastases occur in up to 54% of patients with metastatic tumours
Indexed as
Aspartic AcidLung NeoplasmsProtein BiosynthesisSignal TransductionAnimalsBreast NeoplasmsCell Line, TumorCyclic AMP Response Element-Binding ProteinExtracellular FluidFemaleHumansLungMaleMiceReceptors, N-Methyl-D-AspartateAspartic AcidCyclic AMP Response Element-Binding ProteinReceptors, N-Methyl-D-Aspartate
Identifiers
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LicenceCC BY
Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.