Evidence map›Paper›PMID 39743587›Full record

ArticleNature2025

Learning the fitness dynamics of pathogens from phylogenies.

Noémie Lefrancq, Loréna Duret, Valérie Bouchez, Sylvain Brisse, Julian Parkhill, Henrik Salje

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. A role for genomics-based studies of Bordetella pertussis adaptation.Current opinion in infectious diseases · 2025
    Review
  15. Progressive evolution ofMicrobial genomics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Noémie LefrancqDepartment of Genetics, University of Cambridge, Cambridge, UK. ncmjl2@cam.ac.uk.ORCID 0000-0001-5991-6169
Loréna DuretDepartment of Genetics, University of Cambridge, Cambridge, UK.
Valérie BouchezBiodiversity and Epidemiology of Bacterial Pathogens, Institut Pasteur, Université de Paris, Paris, France.ORCID 0000-0002-5947-6383
Sylvain BrisseBiodiversity and Epidemiology of Bacterial Pathogens, Institut Pasteur, Université de Paris, Paris, France.
Julian Parkhill *Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.ORCID 0000-0002-7069-5958
Henrik Salje *Department of Genetics, University of Cambridge, Cambridge, UK.ORCID 0000-0003-3626-4254

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dynamics of the genetic diversity of pathogens, including the emergence of lineages with increased fitness, is a foundational concept of disease ecology with key public-health implications. However, the identification of such lineages and estimation of associated fitness remain challenging, and is rarely done outside densely sampled systems

Indexed as

Bordetella pertussisGenetic FitnessInfluenza A Virus, H3N2 SubtypeMycobacterium tuberculosisPhylogenySARS-CoV-2Humans

Identifiers

PMID39743587
PMCPMC11735385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.