Evidence map›Paper›PMID 39743542›Full record

ArticleJournal of molecular medicine (Berlin, Germany)2025

VSMC-specific TRPC1 deletion attenuates angiotensin II-induced hypertension and cardiovascular remodeling.

Xin Wen, Yuefeng Peng, Wenqing Yang, Yuzhong Zhu, Fan Yu, Li Geng, Xianfeng Wang, Xiaoyan Wang, Xiaodong Zhang, Yi Tang and 4 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular medicine (Berlin, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xin Wen *Wuxi School of Medicine, Jiangnan University, Jiangsu Province, 1800 Lihu Rd, Wuxi, 214122, China.
Yuefeng Peng *Wuxi School of Medicine, Jiangnan University, Jiangsu Province, 1800 Lihu Rd, Wuxi, 214122, China.
Wenqing YangWuxi School of Medicine, Jiangnan University, Jiangsu Province, 1800 Lihu Rd, Wuxi, 214122, China.
Yuzhong ZhuWuxi School of Medicine, Jiangnan University, Jiangsu Province, 1800 Lihu Rd, Wuxi, 214122, China.
Fan YuWuxi School of Medicine, Jiangnan University, Jiangsu Province, 1800 Lihu Rd, Wuxi, 214122, China.
Li GengWuxi School of Medicine, Jiangnan University, Jiangsu Province, 1800 Lihu Rd, Wuxi, 214122, China.
Xianfeng WangWuxi School of Medicine, Jiangnan University, Jiangsu Province, 1800 Lihu Rd, Wuxi, 214122, China.
Xiaoyan WangDepartment of Cardiology, The Affiliated Hospital of Jiangnan University, Jiangsu Province, No.1000, He Feng Road, Wuxi, 214122, China.
Xiaodong ZhangDepartment of Cardiology, The Affiliated Hospital of Jiangnan University, Jiangsu Province, No.1000, He Feng Road, Wuxi, 214122, China.
Yi TangWuxi School of Medicine, Jiangnan University, Jiangsu Province, 1800 Lihu Rd, Wuxi, 214122, China.
Lei FengWuxi School of Medicine, Jiangnan University, Jiangsu Province, 1800 Lihu Rd, Wuxi, 214122, China.
Tingting ZhouWuxi School of Medicine, Jiangnan University, Jiangsu Province, 1800 Lihu Rd, Wuxi, 214122, China.
Hongliang JiaDepartment of Paediatrics, The Affiliated Hospital of Jiangnan University, Jiangsu Province, No.1000, He Feng Road, Wuxi, 214122, China.
Liu YangWuxi School of Medicine, Jiangnan University, Jiangsu Province, 1800 Lihu Rd, Wuxi, 214122, China. yang221liu@163.com.ORCID http://orcid.org/0000-0003-0169-7471

Funding

Fundamental Research Funds for the Central Universities JUSRP12047Medical Discipline Development Fund, Wuxi School of Medicine, Jiangnan University YXXK2024092601National Natural Science Foundation of China 82100416National Natural Science Foundation of China 82200463National Natural Science Foundation of China 82200532
6 · The paper itself

Abstract

Transient receptor potential canonical 1 (TRPC1) channel, a Ca

Indexed as

Angiotensin IIHypertensionMuscle, Smooth, VascularTRPC Cation ChannelsVascular RemodelingAnimalsCardiomegalyCell ProliferationDisease Models, AnimalEnhancer of Zeste Homolog 2 ProteinGene DeletionMaleMiceMice, Inbred C57BLMice, KnockoutMyocytes, Smooth MuscleAngiotensin IIEnhancer of Zeste Homolog 2 Proteintransient receptor potential cation channel, subfamily C, member 1TRPC Cation ChannelsAngiotensin IIEZH2HypertensionTRPC1Vascular smooth muscle cells

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.