ArticleLipids in health and disease2025
Gender-specific correlations between serum lipid profiles and intra-pancreatic fat deposition: a cross-sectional study.
Article in Lipids in health and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Effects of Metabolic Bariatric Surgery on Intra-pancreatic Fat Deposition and Total Pancreas Volume: a Systematic Review and Meta-analysis.Obesity surgery · 2025Pooled it
- Age-dependent gut microbiota associated with intramuscular fat deposition in Longdong cashmere goats.Animal microbiome · 2026Article
- Article
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8 authors.
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Abstract
backgroundIntra-pancreatic fat deposition (IPFD) is linked to metabolic and pancreatic diseases. MRI, while precise, is not cost-effective for routine IPFD screening, highlighting the need for accessible biomarkers. This study aims to analyze the relationships among serum lipid profiles, lipoprotein ratios, and IPFD, with a focus on sex differences.
methodsData from adults at the Affiliated Hospital of Guizhou Medical University between 2018 and 2019 were analyzed. The subjects underwent routine Siemens 64-slice spiral CT scans, and IPFD was quantified via a quantitative computed tomography post-processing station. Lipid panel components were analyzed in the fasted state. Linear regression models stratified by gender were applied to evaluate these associations.
resultsThe study included 1,046 participants after exclusions, with significant sex differences found in the correlations between serum lipids, lipoprotein ratios, and IPFD. In females, remnant cholesterol was strongly associated with total IPFD (R2 = 0.155, P < 0.001), and similarly strong correlations existed with fat deposition in the pancreatic head (R
conclusionSignificant differences between genders were evident in the correlations of serum lipids and lipoprotein ratios with IPFD. In women, remnant cholesterol was strongly correlated with IPFD, suggesting its potential as a biomarker.
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