Evidence map›Paper›PMID 39743298›Full record

ArticleJournal of Zhejiang University. Science. B2024

Autophagy receptor-inspired chimeras: a novel approach to facilitate the removal of protein aggregates and organelle by autophagy degradation.

Liwen Wang, Huimei Liu, Lanfang Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Zhejiang University. Science. B, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Liwen WangInstitute of Pharmaceutical Pharmacology, School of Pharmacy, University of South China, Hengyang 421001, China.
Huimei LiuHengyang Medical School, University of South China, Hengyang 421001, China.
Lanfang LiInstitute of Pharmaceutical Pharmacology, School of Pharmacy, University of South China, Hengyang 421001, China. 2005001782@usc.edu.cn.

Funding

the Hunan Provincial Natural Science Foundation of China 2023JJ50136the National Natural Science Foundation of China 81970431
6 · The paper itself

Abstract

Neurodegenerative diseases (NDDs), mainly including Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), and Alzheimer's disease (AD), are sporadic and rare genetic disorders of the central nervous system. A key feature of these conditions is the slow accumulation of misfolded protein deposits in brain neurons, the excessive aggregation of which leads to neurotoxicity and further disorders of the nervous system.

Indexed as

AutophagyNeurodegenerative DiseasesProtein AggregatesAlzheimer DiseaseAmyotrophic Lateral SclerosisAnimalsHumansHuntington DiseaseNeuronsOrganellesProtein AggregatesAutophagyOrganellep62Protein aggregatesSynthetic autophagy receptors

Identifiers

PMID39743298
PMCPMC11693386

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.