Evidence map›Paper›PMID 39742884›Full record

ArticleYonsei medical journal2025

Concurrent Association of Multifocality, Bilaterality, and Recurrence in Pediatric Papillary Thyroid Cancer Patients.

Jae Won Cho, Cheong-Sil Rah, Won Woong Kim, Yu-Mi Lee, Seong Chul Kim, Jung Hwan Baek, Dong Eun Song, Won Gu Kim, Ki-Wook Chung, Suck Joon Hong and 1 more

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Article in Yonsei medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jae Won ChoDepartment of Surgery, Asan Medical Center, University of Ulsan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-7775-5159
Cheong-Sil RahDepartment of Surgery, Uijeongbu Eulji Medical Center, Eulji University, Uijeongbu, Korea.ORCID https://orcid.org/0000-0001-8430-3129
Won Woong KimDepartment of Surgery, Asan Medical Center, University of Ulsan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0003-3471-2068
Yu-Mi LeeDepartment of Surgery, Asan Medical Center, University of Ulsan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-8183-2604
Seong Chul KimDepartment of Pediatric Surgery, Asan Medical Center, University of Ulsan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-7803-0475
Jung Hwan BaekDepartment of Radiology, Asan Medical Center, University of Ulsan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0003-0480-4754
Dong Eun SongDepartment of Pathology, Asan Medical Center, University of Ulsan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-9583-9794
Won Gu KimDepartment of Internal Medicine, Asan Medical Center, University of Ulsan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-8404-7759
Ki-Wook ChungDepartment of Surgery, Asan Medical Center, University of Ulsan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-4418-1857
Suck Joon HongDepartment of Surgery, Uijeongbu Eulji Medical Center, Eulji University, Uijeongbu, Korea.ORCID https://orcid.org/0009-0005-1269-3638
Tae-Yon SungDepartment of Surgery, Asan Medical Center, University of Ulsan Medical Center, Seoul, Korea. tysung@amc.seoul.kr.ORCID https://orcid.org/0000-0002-2179-6269

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePediatric papillary thyroid cancer (PTC) is recommended to perform aggressive surgery to reduce the risk of recurrence. This study was designed to evaluate the concurrent association between multifocality, bilaterality, and the risk of recurrence in pediatric PTC. MATERIALS AND

methodsThis retrospective cohort study included pediatric patients (age <19 years) who underwent total thyroidectomy for PTC between 1996 and 2014 in a single tertiary center. Clinicopathological parameters were analyzed to evaluate the prevalence of multifocality, bilaterality, recurrence, and their association.

resultsWe analyzed 58 pediatric patients with PTC. There was no factor related to the presence of multifocality or bilaterality in multivariate analysis. Also, in univariate analysis, multifocality and bilaterality were not independent risk factors of each other's presentation (

conclusionMultifocality and bilaterality were not independent risk factors of each other's presentation; however, multifocality was the risk factor for recurrence in pediatric PTC. For pediatric PTC, close monitoring for recurrence within the initial 4 years is recommended, particularly in patients with clear cell subtype, multifocality, and gross ETE.

Indexed as

Neoplasm Recurrence, LocalThyroid Cancer, PapillaryThyroidectomyThyroid NeoplasmsAdolescentCarcinoma, PapillaryChildChild, PreschoolFemaleHumansMaleMultivariate AnalysisRetrospective StudiesRisk FactorsbilateralitymultifocalityPediatric papillary thyroid cancerrecurrence

Identifiers

PMID39742884
PMCPMC11704237

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.