ArticleEpilepsy & behavior : E&B2025
Development of a rapid screener to elicit patient preferences for antiseizure medication discontinuation.
Article in Epilepsy & behavior : E&B, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Challenges in antiseizure medication discontinuation decisions: A qualitative study of clinicians who see patients with epilepsy.Clinical neurology and neurosurgery · 2026Article
- A mixed-methods study of patient perspectives on antiseizure medication discontinuation attempts after a period of seizure-freedom.BMJ neurology open · 2026Article
- Antiseizure medication discontinuation: A mixed-methods exploration of factors considered by patients when approaching decision-making.Epilepsy research · 2025Article
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Authors and funding
16 authors.
Funding
Abstract
objectiveWhile guidelines encourage individualized discussions of the risks and benefits of antiseizure medication (ASM) withdrawal after a period of seizure-freedom, no formal methods exist for assessing patient preferences. We report the initial development of a rapid patient preferences screener.
methodsWe conducted a mixed-methods study of adults who were ≥1 year seizure-free and seen for epilepsy across three institutions. We reviewed existing questionnaires and adapted three questions measuring core constructs influencing ASM decisions - views about ASMs, driving restrictions, and seizures. We added one additional "global" question, for 4 total questions. Participants rated question clarity and utility from 1 (low) to 7 (high).
resultsOf 32 participants, the median patient age was 46 (interquartile range [IQR] 33-56), with a median 3 years since their last seizure (IQR 2-11). Median responses were: 2 (IQR 1-5) for being bothered by ASMs, 2 (IQR 1-6) for feeling that a driving restriction would be disruptive, and 5 (IQR 4-7) for feeling that another seizure would be serious. Respondents tended to disagree that ASMs are doing more harm than good (median 1, IQR 1-2). Participants rated question clarity (median 6, IQR 6-7) and utility (median 7, IQR 6-7) highly.
conclusionsWe report the initial development of a pre-visit rapid screener of patient preferences pertinent to ASM withdrawal in well-controlled epilepsy. Patients endorsed the utility of such a screener and provided guidance to improve items. We hope that this work will ultimately improve shared decision-making.
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