Evidence map›Paper›PMID 39742525›Full record

ArticleThe American journal of tropical medicine and hygiene2025

Mpox Recrudescence after SARS-CoV-2 Coinfection in a Patient with AIDS.

Yaqing Liu, Shi Zou, Shihui Song, Yingcai Wan, Jianbo Wu, Mingqi Luo, Wei Guo, Ke Liang

Abstract readCase Reports
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yaqing LiuDepartment of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.
Shi ZouDepartment of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.
Shihui SongDepartment of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.
Yingcai WanDepartment of Dermatology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Jianbo WuDepartment of Dermatology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Mingqi LuoDepartment of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.
Wei GuoDepartment of Pathology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Ke LiangDepartment of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

People living with HIV (PLWH) are known to exhibit more severe or prolonged symptoms of mpox (formerly monkeypox). However, the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on PLWH with mpox has not been adequately described. We report a case of mpox in an AIDS patient who had recurrent symptoms due to SARS-CoV-2 infection. The patient presented with a low CD4+ lymphocyte count (CD4 count) without antiretroviral therapy (ART) and suffered from severe mpox. The ART was initiated 17 days after the diagnosis of mpox, and the patient's skin lesions began crusting after 1 week of ART. However, after a SARS-CoV-2 infection, the mpox flared up again. The patient presented with more severe symptoms than those during the initial bout and with rectal involvement. We speculate that SARS-CoV-2 infection might cause a recrudescence of mpox in AIDS patients, which requires further investigation.

Indexed as

Acquired Immunodeficiency SyndromeCoinfectionCOVID-19Mpox, MonkeypoxCD4 Lymphocyte CountHumansMonkeypox virusRecurrenceSARS-CoV-2

Identifiers

PMID39742525
PMCPMC11884265

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.