Evidence map›Paper›PMID 39742254›Full record

ArticleFrontiers in immunology2024

NRF-1 transcription factor regulates expression of an innate immunity checkpoint, CD47, during melanomagenesis.

Kuldeep Makwana, Edwin J Velazquez, Diego M Marzese, Bethany Smith, Neil A Bhowmick, Mark B Faries, Omid Hamid, Alexander D Boiko

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kuldeep MakwanaDepartment of Medicine, Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Edwin J VelazquezDepartment of Medicine, Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Diego M MarzeseDepartment of Surgery, Duke University School of Medicine, Durham, NC, United States.
Bethany SmithDepartment of Medicine, Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Neil A BhowmickDepartment of Medicine, Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Mark B FariesDepartment of Medicine, Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Omid HamidDepartment of Medicine, Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Alexander D BoikoDepartment of Medicine, Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.

Funding

Therapeutic Mechanism of CD47 Blockade in Suppressing Melanoma MetastasisR01CA234892 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI BOIKO, ALEXANDER D · 2020 to 2025
$1.9M
NCI NIH HHS R01 CA234892
6 · The paper itself

Abstract

Transmembrane integrin-associated protein

Indexed as

CD47 AntigenGene Expression Regulation, NeoplasticImmunity, InnateMelanomaNuclear Respiratory Factor 1Promoter Regions, GeneticCell Line, TumorHumansCD47 AntigenCD47 protein, humanNRF1 protein, humanNuclear Respiratory Factor 1cd47immune checkpointmelanomaNRF1promoter regulation

Identifiers

PMID39742254
PMCPMC11685207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.