Evidence map›Paper›PMID 39742167›Full record

ArticleCureus2024

Myasthenia Gravis Complicated by M-proteinemia and Demyelinating Neuropathy: A Report of Two Cases.

Kaiki Kawakita, Takuya Saito, Yoshiyuki Kondo, Tsuyoshi Uchiyama, Keishiro Sato

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In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kaiki KawakitaDepartment of Neurology, Seirei Hamamatsu General Hospital, Hamamatsu, JPN.
Takuya SaitoDepartment of Neurology, Seirei Hamamatsu General Hospital, Hamamatsu, JPN.
Yoshiyuki KondoDepartment of Neurology, Seirei Hamamatsu General Hospital, Hamamatsu, JPN.
Tsuyoshi UchiyamaDepartment of Neurology, Seirei Hamamatsu General Hospital, Hamamatsu, JPN.
Keishiro SatoDepartment of Neurology, Seirei Hamamatsu General Hospital, Hamamatsu, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myasthenia gravis (MG) is characterized by weakness and rapid fatigue of voluntary muscles. Here, we present two cases of early-onset MG, complicated with M-proteinemia and demyelinating neuropathy. Case one was diagnosed with MG at age 29, received tacrolimus post-thymectomy, and developed M-proteinemia and demyelinating neuropathies at age 66 before being diagnosed with B-cell lymphoma. Case two was diagnosed with MG at age 21, received immunosuppressive drugs post-thymectomy, and was diagnosed with myelin-associated glycoprotein antibody-associated neuropathy at age 66. Demyelinating neuropathy with M-proteinuria should be considered when motor symptoms worsen in patients with early-onset MG who receive immunosuppressive drugs after thymectomy.

Indexed as

immunosuppressive agentsm-proteinemiamyasthenia gravisneuropathythymectomy

Identifiers

PMID39742167
PMCPMC11686030

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.