ReviewACS omega2024
Unveiling the Molecular Secrets: A Comprehensive Review of Raman Spectroscopy in Biological Research.
Review in ACS omega, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Accuracy of AI-based raman spectroscopy in the diagnosis of gastric cancer: a systematic review and meta-analysis.Lasers in medical science · 2026Pooled it
- Illuminating glioma surgery: A meta-analysis of Raman spectroscopy for intraoperative decision-making.Neurosurgical review · 2025Pooled it
- Review
- Rice straw sample preparation protocol for cell wall major constituent analysis via Raman spectroscopy.STAR protocols · 2026Article
- SERS-Based Detection of Food Contaminants: From Laboratory Sensitivity to Practical Implementation-Bottlenecks and Pathways to Standardization.Foods (Basel, Switzerland) · 2026Review
- Recent Advances in the Study of Aroma Control and Release Through the Interaction of Matrix Components and Aroma Compounds in Soft Drinks.Journal of food science · 2026Review
- Recent advances in the identification of vaginal fluid for forensic applications.International journal of legal medicine · 2026Review
- Comparative Experimental Raman, DFT, and Chemometric Characterization of Selected Phenolic Acids: Structural and Environmental Contributions to the Vibrational Response.Molecules (Basel, Switzerland) · 2026Article
- Exploratory Serum-Based Surface-Enhanced Raman Spectroscopy Analysis in Crohn's Disease: A Pilot Cross-Sectional Study.International journal of molecular sciences · 2026Article
- Article
- Analysis of Intracellular Fatty Acid Metabolism during Doxorubicin-Induced Senescence of MCF7 Cells Using Raman Imaging.ACS omega · 2026Article
- Raman Investigation of Cardiac Tissues with Sodium-Induced High Stiffness.Molecules (Basel, Switzerland) · 2026Article
- Determination of small peptides in sour meat with Raman spectroscopy and LC-MS/MS.Analytical and bioanalytical chemistry · 2026Article
- Evaluation of cadmium's impact on marine mussels: insights from Raman spectroscopy and chemometric analysis.Analytical and bioanalytical chemistry · 2026Article
- Probing the proteome.eLife · 2026Article
- Quality Analysis and Detection of Adulterants and Contaminations in Milk/Milk Powder by Raman Spectroscopy.Comprehensive reviews in food science and food safety · 2026Review
- Engineering Nanomaterials for Raman Bioimaging and Theranostics: Advances, Challenges, and Future Directions.ACS omega · 2025Review
- Virulence and Stress-Related Proteins Are Differentially Enriched andJournal of fungi (Basel, Switzerland) · 2025Article
- All-trans-retinal as a modulator of metabolic and mitochondrial signatures in non-tumorigenic and malignant breast cells: a Raman-based approach.Mikrochimica acta · 2025Article
- Separation and Detection of Microplastics in Human Exposure Pathways: Challenges, Analytical Techniques, and Emerging Solutions.Journal of xenobiotics · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Raman spectroscopy has been proven to be a fast, convenient, and nondestructive technique for advancing our understanding of biological systems. The Raman effect originates from the inelastic scattering of light which directly probe vibration/rotational states in biological molecules and materials. Despite numerous advantages over infrared spectroscopy and continuous technical as well as operational improvement in Raman spectroscopy, an advanced development of the device and more applications have become possible. In this review, we explore the principles, techniques, and myriad applications of Raman spectroscopy in the realm of biology. We begin by providing an overview of Raman spectroscopy, highlighting its significance in unraveling the complexities of biological research. The focus of this review is on Raman spectroscopy concepts and methods, clarifying the fundamentals of Raman scattering and spectral interpretation. The review also highlights the key experimental considerations for productive biological applications. We explore the broad range of Raman applications including molecular structure, biomolecular composition, disease detection, and medication discovery. The Raman imaging and mapping can also be used to visualize biological samples at the molecular level. Raman spectroscopy is still developing, giving fresh insights and remedies, from biosensing to its use in tissue engineering and regenerative medicine. This review sheds light on the past, present, and future of Raman spectroscopy; it also highlights promising directions of future research developments and serves as a thorough resource for all researchers.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.