ArticleProceedings of SPIE--the International Society for Optical Engineering2020
Determining the Optimal Angular Range of the X-Ray Source Motion in Tomosynthesis Using Virtual Clinical Trials.
Article in Proceedings of SPIE--the International Society for Optical Engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Line-based iterative geometric calibration method for a tomosynthesis system.Medical physics · 2024Article
- Signal-to-Noise Ratio and Contrast-to-Noise Ratio Measurements for Next Generation Tomosynthesis.Proceedings of SPIE--the International Society for Optical Engineering · 2021Article
- Super-Resolution in Digital Breast Tomosynthesis: Limitations of the Conventional System Design and Strategies for Optimization.Proceedings of SPIE--the International Society for Optical Engineering · 2020Article
- Achieving Isotropic Super-Resolution with a Non-Isocentric Acquisition Geometry in a Next-Generation Tomosynthesis System.Proceedings of SPIE--the International Society for Optical EngineeringArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
The limited angle and limited number of projections in digital breast tomosynthesis (DBT) produce under-sampled datasets that may compromise calcification detection. Small breast lesions, such as microcalcifications, may not be discernible without sufficient sampling in the reconstructed DBT images. We propose a virtual clinical trial (VCT) method to evaluate the calcification detection in DBT using computer simulations of breast phantoms, images, and virtual readers. We used multiple-reader multiple-case (MRMC) receiver operating characteristic (ROC) analyses to evaluate the performance of channelized Hotelling observers (CHOs) in calcification detection. The angular motion path of the x-ray source was varied to simulate different DBT acquisition geometries. We simulated continuous and step-and-shoot x-ray source motion and three angular motion paths: ±7.5°, ±15°, and ±25°. The detection of calcifications is affected by the angular motion path, particularly for the ±25° angular range, combined with continuous tube motion, larger detector element sizes (0.14 mm) and larger reconstructed voxel sizes (0.10 mm). When an angular range of ±25° is compared to ±7.5°, the difference in the area under the curve (AUC) is -0.030 (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.