Evidence map›Paper›PMID 39741611›Full record

ArticleCureus2024

Assessment of Vitamin E and Glutathione Peroxidase Levels in Salivary Samples of Children With and Without Dental Caries in Erbil City, Iraq.

Pareehan M Hussein, Vian M Hussein

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pareehan M HusseinDental Surgery, Hawler Center, Erbil, IRQ.
Vian M HusseinDental Public Health, Kurdistan Higher Council of Medical Specialties, Erbil, IRQ.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAccording to the classic understanding of the etiology of dental caries, an imbalance between demineralization and remineralization in the oral cavity is important. Salivary antioxidants, including glutathione peroxidase and vitamin E, can modulate oxidative stress.

methodsThis cross-sectional study evaluated the levels of glutathione peroxidase and vitamin E in the saliva of 90 children from Erbil City. The children were further subdivided based on their caries status and membership in the caries-free group. SPSS software was used for statistical comparisons.

resultsThe difference in antioxidant levels between the groups was statistically significant. In children, a significant decrease in the levels of glutathione (1664.356 µM) and vitamin E (4.0844 nM) in caries-susceptible individuals was observed compared to those not affected by caries (glutathione, 1945.355 µM; vitamin E, 5.3240 nM).

conclusionThe study postulates that lower levels of antioxidants are associated with dental caries and highlights the potential of glutathione and vitamin E for oral health protection. This calls for further exploration of the usefulness of these antioxidants as potential therapeutic mediators for dental care.

Indexed as

childerendental cariesglutathione peroxidasesalivary samplesvitamin e

Identifiers

PMID39741611
PMCPMC11685327

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.