ArticleJournal of pharmacopuncture2024
In Vitro Assays for the Assessment of Safety and Toxicity in Pharmacopuncture Derived from Animal.
Article in Journal of pharmacopuncture, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Among the various treatment methods involving the use of natural substances, pharmacopuncture using animal venom is a relatively new form of acupuncture that has been developed in South Korea and is gaining popularity worldwide. Pharmacopuncture with animal venom is widely used in clinical practice; therefore, ensuring its procedural safety is crucial. This study aimed to evaluate the safety and toxicity of pharmacopuncture using animal venom. Methods: In October 2021, nine samples of animal venom-derived pharmacopuncture products were randomly collected from four External Herbal Dispensaries (EHDs). These samples underwent sterility and microbial limit testing to ensure they were free from microbial contamination. Toxicity tests were conducted using three different cell lines to evaluate cytotoxic effects. Results: The sterility and microbial limit tests showed no microbial growth in any of the pharmacopuncture samples. However, the toxicity tests revealed that bee venom exhibited strong cytotoxicity. Furthermore, samples containing Bovis Calculus, Fel Ursi, and Moschus also demonstrated varying degrees of cytotoxic effects. Conclusion: This study is the first to analyze the safety and toxicity of animal venom-derived pharmacopuncture products, providing evidence for its procedural safety. Although the samples analyzed were limited to four EHDs, these findings highlight the importance of further research on the safety and toxicity of pharmacopuncture to ensure its clinical application is both effective and safe.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.