Evidence map›Paper›PMID 39741567›Full record

ArticleJournal of pharmacopuncture2024

Cannabigerol Treatment Shows Antiproliferative Activity and Causes Apoptosis of Human Colorectal Cancer Cells.

Ju-Hee Park, Yu-Na Hwang, Han-Heom Na, Do-Yeon Kim, Hyo-Jun Lee, Tae-Hyung Kwon, Jin-Sung Park, Keun-Cheol Kim

Abstract read
In one paragraph

Article in Journal of pharmacopuncture, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ju-Hee ParkDepartment of Biological Sciences, College of Natural Sciences, Kangwon National University, Chuncheon, Republic of Korea.ORCID https://orcid.org/0009-0004-3060-6107
Yu-Na HwangDepartment of Biological Sciences, College of Natural Sciences, Kangwon National University, Chuncheon, Republic of Korea.ORCID https://orcid.org/0000-0002-5250-6375
Han-Heom NaDepartment of Biological Sciences, College of Natural Sciences, Kangwon National University, Chuncheon, Republic of Korea.ORCID https://orcid.org/0000-0003-3753-3129
Do-Yeon KimDepartment of Biological Sciences, College of Natural Sciences, Kangwon National University, Chuncheon, Republic of Korea.ORCID https://orcid.org/0009-0003-3810-389X
Hyo-Jun LeeDepartment of Biological Sciences, College of Natural Sciences, Kangwon National University, Chuncheon, Republic of Korea.ORCID https://orcid.org/0009-0002-6119-8252
Tae-Hyung KwonChuncheon Bioindustry Foundation, Chuncheon, Republic of Korea.ORCID https://orcid.org/0000-0002-2250-9444
Jin-Sung ParkKorean Pharmacopuncture Institute, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-1963-3938
Keun-Cheol KimDepartment of Biological Sciences, College of Natural Sciences, Kangwon National University, Chuncheon, Republic of Korea.ORCID https://orcid.org/0000-0003-3047-0380

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To determine growth inhibitory and anti-cancer effects of Cannabigerol (CBG) in human colorectal cancer cells. Methods: Anti-proliferative effect of CBG was examined using MTT assay and two colorectal cancer cells (SW480 and LoVo cells). Cell death ratio was analyzed using Annexin V/PI staining experiment. Cell cycle distribution was analyzed using flow cytometry. We also performed western blot analysis on apoptotic marker proteins. Results: CBG showed growth inhibitory effect in colorectal cancer cells using MTT assay. IC Conclusion: CBG treatment shows antiproliferative activity and causes apoptosis of colorectal cancer cells, suggesting that CBG is applicable as a promising anticancer drug.

Indexed as

apoptosiscannabigerolcolorectal cancerIC50phytocannabinoid

Identifiers

PMID39741567
PMCPMC11656058

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.