Evidence map›Paper›PMID 39741512›Full record

ArticleFrontiers in medicine2024

Haptoglobin 2-2 genotype is associated with increased risk of cardiovascular disease in patients with rheumatoid arthritis: a matched case-control study.

Chuanhui Xu, Lay Wai Khin, Hui Zhen Tam, Liuh Ling Goh, Ee Tzun Koh, Rinkoo Dalan, Khai Pang Leong

Abstract read
In one paragraph

Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chuanhui XuDepartment of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore, Singapore.
Lay Wai KhinClinical Research & Innovation Office, Tan Tock Seng Hospital, Singapore, Singapore.
Hui Zhen TamClinical Research & Innovation Office, Tan Tock Seng Hospital, Singapore, Singapore.
Liuh Ling GohMolecular Diagnostic Laboratory, Tan Tock Seng Hospital, Singapore, Singapore.
Ee Tzun KohDepartment of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore, Singapore.
Rinkoo DalanLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Khai Pang LeongDepartment of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Traditional risk factors do not fully explain the increased risk of cardiovascular disease (CVD) in patients with rheumatoid arthritis (RA). The Methods: Data from 69 RA patients with CVD and 207 sex- and ethnicity-matched RA patients without CVD, collected from 1 January 2000 to 31 December 2020, were retrieved from the Tan Tock Seng Hospital RA Registry. CVD was examined against demographics, clinical and laboratory variables in univariate models. Associations between the Results: We studied 276 patients (65.2% female, 82.6% Chinese, median age 60.9 years). Most participants were in low disease activity or remission (79.3%). The Conclusion: The

Indexed as

cardiovascular diseaseHaptoglobin genotypesinflammationpersonalized medicinerheumatoid arthritis

Identifiers

PMID39741512
PMCPMC11685008

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.