Evidence map›Paper›PMID 39741389›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Defluorinative Cyclization of Enamides with Fluoroalkyl Halides Through Two Vicinal C(sp

Yu-Lan Chen, Wei Han, Yuan-Yuan Ren, Mengtao Ma, Danhua Ge, Zhi-Liang Shen, Kai Guo, Xue-Qiang Chu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Defluorinative Cyclization of Enamides with Fluoroalkyl Halides Through Two Vicinal C(spAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yu-Lan ChenTechnical Institute of Fluorochemistry, School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing, 211816, China.
Wei HanTechnical Institute of Fluorochemistry, School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing, 211816, China.
Yuan-Yuan RenTechnical Institute of Fluorochemistry, School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing, 211816, China.
Mengtao MaDepartment of Chemistry and Materials Science, College of Science, Nanjing Forestry University, Nanjing, 210037, China.
Danhua GeTechnical Institute of Fluorochemistry, School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing, 211816, China.
Zhi-Liang ShenTechnical Institute of Fluorochemistry, School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing, 211816, China.ORCID https://orcid.org/0000-0002-3365-9288
Kai GuoCollege of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, 211816, China.
Xue-Qiang ChuTechnical Institute of Fluorochemistry, School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing, 211816, China.

Funding

Nanjing Tech UniversityNational Natural Science Foundation of China 21772093National Natural Science Foundation of China 22001121Postgraduate Research & Practice Innovation Program of Jiangsu Province KYCX23_1401
6 · The paper itself

Abstract

Introducing distinctive functional groups to expand the structural diversity and improve the intrinsic properties of parent molecules has been an essential pursuit in organic chemistry. By using perfluoroalkyl halide (PFAH) as a nontraditional, readily available, ideal 1,2-difluoroalkenyl coupling partner, a defluorinative cyclization reaction of enamides for the construction of fluoroalkenyl oxazoles is first developed. The selective and controllable two-fold cleavage of vicinal C(sp

Indexed as

1,2‐difluoroalkenyl groupC─F bond functionalizationdefluorinative cyclizationfluoroalkyl halidesoxazole

Identifiers

PMID39741389
PMCPMC11848561

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.