Evidence map›Paper›PMID 39741382›Full record

ArticleACS infectious diseases2025

Development of CGS-15943 Adjunctives for the Disruption of Plasmid Maintenance in Multidrug Resistant

Mintesinot Kassu, Katelyn E Zulauf, Jessica N Ross, James E Kirby, Roman Manetsch

Abstract read
In one paragraph

Article in ACS infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mintesinot KassuDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States.
Katelyn E ZulaufDepartment of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, United States.
Jessica N RossDepartment of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, United States.
James E KirbyDepartment of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, United States.
Roman ManetschDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States.ORCID 0000-0001-7038-6867

Funding

INFECTIOUS DISEASE AND BASIC MICROBIOLOGICAL MECHANISMST32AI007061 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Marcia B Goldberg · 1985 to 2026
$12.1M
Plasmid Eviction to Restore Susceptibility in Carbapenem-Resistant EnterobacteriaceaeR33AI119114 · NIAID · BETH ISRAEL DEACONESS MEDICAL CENTER · PI KIRBY, JAMES E · 2017 to 2019
$1.5M
Identification and Characterization of Novel Antimicrobial Adjunctives to Restore Susceptibility to Carbapenem Resistant EnterobacteriaceaeF32AI124590 · NIAID · BETH ISRAEL DEACONESS MEDICAL CENTER · PI SMITH, KENNETH PATRICK · 2017 to 2019
$175k
NIAID NIH HHS F32 AI124590NIAID NIH HHS R33 AI119114NIAID NIH HHS T32 AI007061
6 · The paper itself

Abstract

Carbapenemase producing

Indexed as

Anti-Bacterial AgentsDrug Resistance, Multiple, BacterialEscherichia coliMicrobial Sensitivity TestsPlasmidsBacterial Outer Membrane ProteinsEscherichia coli K12Escherichia coli ProteinsMembrane Transport ProteinsAnti-Bacterial AgentsBacterial Outer Membrane ProteinsEscherichia coli ProteinsMembrane Transport ProteinstolC protein, E coliadjunctivecarbapenemasecarbapenemase producing EnterobacteralesCarbapenem resistant EnterobacteralesCGS-15943multidrug-resistanceplasmid

Identifiers

PMID39741382
PMCPMC11731274

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.