ArticleBMC endocrine disorders2024
Thyroid function, autoimmunity, thyroid volume, and metabolic profile in people with Hashimoto thyroiditis.
Article in BMC endocrine disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Hypoxia-Inducible Factor 1-α in Autoimmune Diseases-Insights from the Paradigm of Hashimoto's Thyroiditis: A Narrative Review.Medical sciences (Basel, Switzerland) · 2026Review
- Thyroid follicular cell-derived GDF15 attenuates inflammation and lipid dysregulation in Hashimoto's thyroiditis.Frontiers in medicine · 2026Article
- Heterozygous pathogenic variants inOpen life sciences · 2026Article
- Comparison of triglyceride-glucose index and atherogenic index of plasma in euthyroid Hashimoto's thyroiditis patients and healthy controls.BMC endocrine disorders · 2025Article
- Article
- Exploration of post-PEG precipitation TSH recovery in hypothyroid patients.Frontiers in endocrinology · 2025Article
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Authors and funding
4 authors.
Funding
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Abstract
backgroundHashimoto's thyroiditis (HT) is associated with high cardiovascular risk. Thyroid volume has a notable dispersion of values in these patients. This study aims to clarify the association between thyroid antibodies, thyroid morphology, insulin resistance, and lipid profile in patients with HT.
methodsCross-sectional study that includes 409 subjects diagnosed with HT. We assessed thyroid function, markers of autoimmunity, and markers of cardiovascular risk. We also evaluated thyroid ultrasound and studied the correlation between all factors.
resultsAmong the study population, 9.8% were male, the mean age was 56.4 ± 17.4 years, 63.7% had dyslipidemia, and 29.5% had diabetes. Patients with hypothyroidism had higher levels of anti-thyroperoxidase antibodies (TPOab), and the decreased thyroid dimensions subgroup had a higher percentage of patients taking levothyroxine (98.7%). Positive correlations were found between TPOab and volume, and negative correlations were observed between thyroid-stimulating hormone (TSH) and volume.
conclusionThe current study reveals a complex interrelationship between cardiovascular disease risk factors, thyroid function, autoimmunity, and thyroid volume in HT. These associations may be of clinical relevance, and further studies are needed to elucidate how these findings may be used clinically to reduce the cardiovascular risk in patients with HT.
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