ArticleCommunications medicine2024
The impact of gender-affirming interventions on eating disorder diagnosis risk among transgender and gender-diverse individuals.
Article in Communications medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Exploring the Intersection of Gender Identity and Eating Behaviours in Gender-Diverse Populations.European eating disorders review : the journal of the Eating Disorders Association · 2026Article
- Investigation of associations between self-reported sensory processing, eating disorder symptoms, neurodivergence, and gender congruence from a lived experience lens.Journal of eating disorders · 2026Article
- Eating behaviors in transmasculine and transfeminine adults assessed by the three factor eating questionnaire.Frontiers in nutrition · 2026Article
- Disordered eating in autistic trans and gender diverse people: a lived experience-led scoping review.Journal of eating disorders · 2025Review
- Inclusive Nutrition Care for LGBT+ Patients: Challenges and Opportunities for Dietitians-A Narrative Review.Nutrients · 2025Review
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
backgroundThe objective of this study is to evaluate the risk of being diagnosed with an eating disorder among transgender and gender-diverse (TGD) individuals, specifically examining how this risk differs following gender-affirming medical therapy (GAMT).
methodsThe study utilizes electronic medical record (EMR) data from the TriNetX database. A total of 90,955 TGD individuals were identified in the TriNetX database. TGD individuals were divided into cohorts according to gender-affirming interventions they received. To assess the risk of eating disorder diagnoses across groups, we applied a Cox proportional hazards model with gender-affirming care as a time-varying covariate.
resultsHere we show that transfeminine individuals receiving hormone therapy (HT) have a significantly higher likelihood of being diagnosed with an eating disorder compared to those without intervention (HR:1.67, 95% CI:1.41, 1.98). Conversely, transmasculine individuals on HT exhibit a reduced risk of being diagnosed with an eating disorder relative to those without intervention (HR: 0.83, 95% CI: 0.76, 0.90).
conclusionsAfter undergoing gender-affirming medical therapy, the risk of eating disorder diagnosis increases for transfeminine individuals and decreases for transmasculine individuals. The observed differences in risk between transfeminine and transmasculine individuals on GAMT may be attributed to factors such as gendered societal norms, variations in screening practices, and the physiological effects of hormone therapy on eating disorder symptomatology. Further research is needed to clarify these influences and support tailored interventions.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.