SynthesisMolecular psychiatry2025
Unraveling the associations between voice pitch and major depressive disorder: a multisite genetic study.
Synthesis in Molecular psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic narrative review of the form, process, and function of sensory hyposensitivity in depression.Translational psychiatry · 2026Pooled it
- Performance of Automatic Speech Analysis in Detecting Depression: Systematic Review and Meta-Analysis.JMIR mental health · 2025Pooled it
- Impaired glymphatic function is associated with synaptic loss in cognitive impairment.European journal of nuclear medicine and molecular imaging · 2026Article
- Cross-Cultural Identification of Acoustic Voice Features for Depression: A Cross-Sectional Study of Vietnamese and Japanese Datasets.Bioengineering (Basel, Switzerland) · 2025Article
- Automated Speech Analysis for Screening and Monitoring Bipolar Depression: Machine Learning Model Development and Interpretation Study.JMIR medical informatics · 2025Article
- Listening to the Mind: Integrating Vocal Biomarkers into Digital Health.Brain sciences · 2025Article
- Association of objective subtle cognitive difficulties with amyloid-β and tau deposition compared to subjective cognitive decline.European journal of nuclear medicine and molecular imaging · 2025Article
- Depression diagnosis from patient interviews using multimodal machine learning.Frontiers in psychiatry · 2025Article
- Genetic association analysis of human median voice pitch identifies a common locus for tonal and non-tonal languages.Communications biology · 2024Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Major depressive disorder (MDD) often goes undiagnosed due to the absence of clear biomarkers. We sought to identify voice biomarkers for MDD and separate biomarkers indicative of MDD predisposition from biomarkers reflecting current depressive symptoms. Using a two-stage meta-analytic design to remove confounds, we tested the association between features representing vocal pitch and MDD in a multisite case-control cohort study of Chinese women with recurrent depression. Sixteen features were replicated in an independent cohort, with absolute association coefficients (beta values) from the combined analysis ranging from 0.24 to 1.07, indicating moderate to large effects. The statistical significance of these associations remained robust, with P values ranging from 7.2 × 10
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.