ArticleBMJ open2024
Determining the effect of seminal plasma supplementation on sperm motility in males with asthenozoospermia: a systematic review protocol.
Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Spinal Cord Injury-Related Male Infertility: Oxidative Stress, Inflammation, and Sperm DNA Damage.Journal of clinical medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMale infertility, defined as the inability to impregnate a fertile female, arises from various factors, among which sperm motility plays a pivotal role in determining reproductive potential. Seminal plasma, a complex fluid comprising diverse proteins, serves to nourish and support sperm, thereby facilitating their function within the female reproductive tract for successful conception. Normozoospermia denotes normal sperm motility in males, whereas asthenozoospermia indicates reduced sperm motility. This review seeks to assess the feasibility of augmenting sperm motility in men with asthenozoospermia through supplementation with seminal plasma or specific seminal plasma proteins. METHODS AND ANALYSIS: A systematic literature review following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines will be conducted. PubMed and Google Scholar databases will be systematically searched using predefined keywords and Boolean operators. The search strategy will encompass terms related to asthenozoospermia, normozoospermia, seminal plasma proteins, sperm motility and sperm movement. Additionally, reference lists of relevant articles will be scrutinised for additional studies. Inclusion criteria will encompass human studies published as original research articles between 2019 and 2023. Data extraction will be performed using a standardised form, encompassing author details, country of origin, publication year, study design, participant characteristics, outcomes and conclusions. The risk of bias within the selected studies will be evaluated using the Robvis visualisation tool. ETHICS AND DISSEMINATION: Ethical approval is not required for this systematic review. The findings will be disseminated through publication in a peer-reviewed scientific journal and presentation at relevant conferences. PROSPERO REGISTRATION NUMBER: CRD42024526439.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.