Evidence map›Paper›PMID 39740343›Full record

Observational studyAlzheimer's & dementia : the journal of the Alzheimer's Association2025

Applying recommendations for diagnostic disclosure of mild cognitive impairment and dementia: Practical guidance for clinicians.

Kyra O'Brien, Emily A Largent, Jason Karlawish

Abstract readObservational Study
In one paragraph

Observational study in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Guideline
  4. Review
  5. Review
  6. Article
  7. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kyra O'BrienDepartment of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Emily A LargentDepartment of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Jason KarlawishDepartment of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

Funding

Research Education ComponentP30AG072979 · NIA · UNIVERSITY OF PENNSYLVANIA · PI DAVID A WOLK · 2021 to 2026
$24.8M
NIA NIH HHS P30 AG072979
6 · The paper itself

Abstract

A comprehensive evaluation for cognitive impairment should culminate with the communication of the diagnosis to patients and their care partners. This diagnostic disclosure sets the stage for subsequent care. Diagnostic disclosure for individuals with cognitive impairment due to Alzheimer's disease (AD) or AD-related dementias (ADRD) is particularly nuanced and requires a conscientious approach. Clinicians must assess patients' understanding and appreciation of symptoms, goals for the evaluation, and desire for information. Because AD/ADRD can impact patients' perceptions of their symptoms, it is recommended to include an informant or care partner for this assessment and for future care. Here, we provide guidance for addressing the complexities of AD/ADRD diagnostic disclosure to build clinicians' confidence in communicating diagnostic findings and a plan of care. HIGHLIGHTS: Diagnostic disclosure is a key part of the evaluation of cognitive impairment. The disclosure process begins at the moment a cognitive evaluation is initiated. Care partners must be included in the cognitive evaluation and diagnostic disclosure. Clinicians should use patient-centered communication for evaluation and disclosure.

Indexed as

Alzheimer DiseaseCognitive DysfunctionDementiaDisclosureTruth DisclosureCaregiversCommunicationHumansAlzheimer's disease and related dementiasdementiadiagnostic disclosuremild cognitive impairment

Identifiers

PMID39740343
PMCPMC11772705

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.