Evidence map›Paper›PMID 39740266›Full record

ReviewCurrent opinion in neurobiology2025

Zebrafish as a model to understand extraocular motor neuron diversity.

Celine Bellegarda, Franziska Auer, David Schoppik

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Vertical optokinetic eye movements in the larval zebrafish.The Journal of experimental biology · 2026
    Article
  3. Transcriptional profiling of extraocular motor neurons revealsbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Celine BellegardaDepartments of Otolaryngology, Neuroscience, and the Neuroscience Institute, NYU Grossman School of Medicine, USA.
Franziska AuerDepartments of Otolaryngology, Neuroscience, and the Neuroscience Institute, NYU Grossman School of Medicine, USA.
David SchoppikDepartments of Otolaryngology, Neuroscience, and the Neuroscience Institute, NYU Grossman School of Medicine, USA. Electronic address: schoppik@gmail.com.

Funding

Training Program in Molecular, Cellular, and Translational NeuroscienceT32NS086750 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI JEREMY S DASEN, Katherine Nagel · 2014 to 2026
$2.4M
Determinants of extraocular motor neuron subtype diversityR01EY035691 · NEI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI David Schoppik · 2024 to 2026
$1.5M
NEI NIH HHS R01 EY035691NINDS NIH HHS T32 NS086750
6 · The paper itself

Abstract

Motor neurons have highly diverse anatomical, functional and molecular features, and differ significantly in their susceptibility in disease. Extraocular motor neurons, residing in the oculomotor, trochlear and abducens cranial nuclei (nIII, nIV and nVI), control eye movements. Recent work has begun to clarify the developmental mechanisms by which functional diversity among extraocular motor neurons arises. However, we know little about the role and consequences of extraocular motor neuron diversity in eye movement control. Here, we highlight recent work investigating the anatomical, functional and molecular features of extraocular motor neurons. Further, we frame hypotheses where studying ocular motor circuits in the larval zebrafish is poised to illuminate the consequences of motor neuron diversity for behavior.

Indexed as

Eye MovementsModels, AnimalMotor NeuronsOculomotor MusclesZebrafishAnimals

Identifiers

PMID39740266
PMCPMC11839329

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.