Evidence map›Paper›PMID 39739598›Full record

ArticleMedical care2025

Facility-Level Differences in Antipsychotic Drug Use: Impact on Quality Outcomes for Nursing Home Residents.

Amanda C Chen, David C Grabowski

Abstract read
In one paragraph

Article in Medical care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Amanda C ChenGraduate School of Arts and Sciences, Harvard University, Cambridge, MA.ORCID 0000-0003-3933-8570
David C GrabowskiDepartment of Health Care Policy, Harvard Medical School, Boston, MA.

Funding

Tradeoffs in the Design of Public Long-Term Care BenefitsP01AG032952 · NIA · HARVARD MEDICAL SCHOOL · PI Leila S. Agha · 2009 to 2026
$39.0M
NIA NIH HHS P01 AG032952
6 · The paper itself

Abstract

objectiveTo quantify quality of care following an admission to a nursing home with low or high antipsychotic drug use.

backgroundMisuse of antipsychotics in U.S. nursing homes is a huge concern for policymakers.

methodsWe utilized an instrumental variable approach to estimate the effect of facility-level antipsychotic use on patient outcomes. The instrument was the differential distance to the nearest low-use antipsychotic nursing home relative to the nearest high-use antipsychotic nursing home. Post-acute care short-stay and long-stay residents in U.S. nursing homes were identified using Medicare administrative claims and the Minimum Dataset 3.0 (2014-2019). Outcomes included hospitalizations, falls, pressure ulcers, physical restraint use, medication use, and diagnosis of schizophrenia, bipolar disease, anxiety, or depression.

resultsAmong long-stay residents, receiving care from a low-use facility reduced the diagnosis of schizophrenia, use of restraints, and hospitalizations. There was also a reduction in the hospitalization rate [-0.9 percentage point (pp)], likelihood of long-stay status (-1.8 pp), and diagnosis of schizophrenia (-0.2 pp) at 90 days among short-stay residents. We also observed larger reductions among residents with dementia and serious mental illness.

conclusionsAdmission to a nursing home with a low use of antipsychotics led to decreased hospitalizations, restraint use, and diagnosis of schizophrenia. Curbing the high use of antipsychotics remains a priority of policymakers as the centers for medicare and medicaid services conducts off-site audits to assess whether nursing homes accurately code residents with schizophrenia. It will be important to monitor if centers for medicare and medicaid services downgrades any quality star ratings due to inappropriate coding and assess the implications on quality of care.

Indexed as

Antipsychotic AgentsNursing HomesQuality of Health CareAgedAged, 80 and overFemaleHospitalizationHumansMaleMedicareRestraint, PhysicalUnited StatesAntipsychotic Agents

Identifiers

PMID39739598
PMCPMC12148333

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.