Evidence map›Paper›PMID 39739441›Full record

GuidelineCancer communications (London, England)2025

The Chinese Society of Clinical Oncology (CSCO): Clinical guidelines for the diagnosis and treatment of colorectal cancer, 2024 update.

Feng Wang, Gong Chen, Zhen Zhang, Ying Yuan, Yi Wang, Yuan-Hong Gao, Weiqi Sheng, Zixian Wang, Xinxiang Li, Xianglin Yuan and 20 more

Abstract readPractice Guideline
In one paragraph

Guideline in Cancer communications (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Feng WangDepartment of Medical Oncology, Sun Yat-sen University Cancer Center, The State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Research Unit of Precision Diagnosis and Treatment for Gastrointestinal Cancer, Chinese Academy of Medical Sciences, Guangzhou, Guangdong, P. R. China.ORCID https://orcid.org/0000-0001-7668-9674
Gong ChenDepartment of Colorectal Surgery, Sun Yat-sen University Cancer Center, The State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, Guangdong, P. R. China.
Zhen ZhangDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, P. R. China.
Ying YuanDepartment of Medical Oncology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P. R. China.ORCID https://orcid.org/0000-0002-3922-9553
Yi WangDepartment of Radiology, Peking University People's Hospital, Beijing, P. R. China.
Yuan-Hong GaoDepartment of Radiation Oncology, Sun Yat-sen University Cancer Centre, The State Key Laboratory of Oncology in South China, Guangzhou, Guangdong, P. R. China.
Weiqi ShengDepartment of Pathology, Fudan University Shanghai Cancer Center, Shanghai, P. R. China.
Zixian WangDepartment of Medical Oncology, Sun Yat-sen University Cancer Center, The State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Research Unit of Precision Diagnosis and Treatment for Gastrointestinal Cancer, Chinese Academy of Medical Sciences, Guangzhou, Guangdong, P. R. China.ORCID https://orcid.org/0000-0002-7950-787X
Xinxiang LiDepartment of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, P. R. China.
Xianglin YuanDepartment of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P. R. China.
Sanjun CaiDepartment of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, P. R. China.
Li RenDepartment of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, P. R. China.
Yunpeng LiuDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang, Liaoning, P. R. China.
Jianmin XuDepartment of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, P. R. China.ORCID https://orcid.org/0000-0001-5441-8240
Yanqiao ZhangDepartment of Oncology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, P. R. China.
Houjie LiangDepartment of Oncology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, P. R. China.ORCID https://orcid.org/0000-0002-5924-7783
Xicheng WangDepartment of Gastrointestinal Oncology, Cancer Medical Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Aiping ZhouDepartment of Medical Oncology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P. R. China.
Jianming YingDepartment of Pathology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P. R. China.
Guichao LiDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, P. R. China.
Muyan CaiDepartment of Pathology, Sun Yat-sen University Cancer Center, The State Key Laboratory of Oncology in South China, Guangzhou, Guangdong, P. R. China.ORCID https://orcid.org/0000-0002-4646-4391
Gang JiDepartment of Gastrointestinal Surgery, Xijing Hospital, Air Force Military Medical University, Xi'an, Shaanxi, P. R. China.
Taiyuan LiDepartment of General Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, P. R. China.
Jingyu WangDepartment of Radiology, The First Hospital of Jilin University, Changchun, Jilin, P. R. China.
Hanguang HuDepartment of Medical Oncology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P. R. China.
Kejun NanDepartment of Medical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China.
Liuhong WangDepartment of Radiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P. R. China.
Suzhan ZhangDepartment of Colorectal Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P. R. China.
Jin LiDepartment of Medical Oncology, Shanghai GoBroad Cancer Hospital, China Pharmaceutical University, Shanghai, P. R. China.
Rui-Hua XuDepartment of Medical Oncology, Sun Yat-sen University Cancer Center, The State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University, Research Unit of Precision Diagnosis and Treatment for Gastrointestinal Cancer, Chinese Academy of Medical Sciences, Guangzhou, Guangdong, P. R. China.ORCID https://orcid.org/0000-0001-9771-8534

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 2024 updates of the Chinese Society of Clinical Oncology (CSCO) Clinical Guidelines for the diagnosis and treatment of colorectal cancer emphasize standardizing cancer treatment in China, highlighting the latest advancements in evidence-based medicine, healthcare resource access, and precision medicine in oncology. These updates address disparities in epidemiological trends, clinicopathological characteristics, tumor biology, treatment approaches, and drug selection for colorectal cancer patients across diverse regions and backgrounds. Key revisions include adjustments to evidence levels for intensive treatment strategies, updates to regimens for deficient mismatch repair (dMMR)/ microsatellite instability-high (MSI-H) patients, proficient mismatch repair (pMMR)/ microsatellite stability (MSS) patients who have failed standard therapies, and rectal cancer patients with low recurrence risk. Additionally, recommendations for digital rectal examination and DNA polymerase epsilon (POLE)/ DNA polymerase delta 1 (POLD1) gene mutation testing have been strengthened. The 2024 CSCO Guidelines are based on both Chinese and international clinical research, as well as expert consensus, ensuring their relevance and applicability in clinical practice, while maintaining a commitment to scientific rigor, impartiality, and timely updates.

Indexed as

Colorectal NeoplasmsMedical OncologyChinaDNA Mismatch RepairHumansMicrosatellite InstabilityPrecision MedicineSocieties, MedicaladjuvantchemotherapyChinese Society of Clinical Oncology (CSCO)colorectal cancerdiagnosisimmunotherapyneoadjuvantradiotherapysurgerytargeted therapy

Identifiers

PMID39739441
PMCPMC11947620

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.