Evidence map›Paper›PMID 39739310›Full record

ReviewJournal of the American Geriatrics Society2025

Clin-STAR Corner: Practice Changing Advances at the Interface of Oncology and Geriatrics.

Tanyanika Phillips, Jingran Ji, Vani Katheria, William Dale

Abstract readReview
In one paragraph

Review in Journal of the American Geriatrics Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tanyanika PhillipsDepartment of Medical Oncology, City of Hope, Duarte, California, USA.ORCID 0000-0003-0719-8083
Jingran JiDepartment of Medical Oncology, City of Hope, Duarte, California, USA.
Vani KatheriaCenter for Cancer and Aging, City of Hope, Duarte, California, USA.
William DaleCenter for Cancer and Aging, City of Hope, Duarte, California, USA.

Funding

Clin-STAR Coordinating CenterU24AG065204 · NIA · AMERICAN FEDERATION FOR AGING RESEARCH · PI Thomas Michael Gill, Kristine Yaffe · 2019 to 2026
$5.5M
Geriatric Oncology Research Infrastructure to Improve Clinical CareR33AG059206 · NIA · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI WILLIAM DALE, Heidi Diana Klepin · 2020 to 2026
$5.1M
Mentoring the Next Generation of Geriatric Oncology Researchers in Patient-Oriented Research to Improve the Care of Older Adults with CancerK24AG055693 · NIA · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI WILLIAM DALE · 2018 to 2026
$1.4M
NIA NIH HHS K24 AG055693NIA NIH HHS K24AG055693NIA NIH HHS R33 AG059206NIA NIH HHS U24 AG065204
6 · The paper itself

Abstract

Cancer and aging are inextricably linked, and older adults are a significant proportion of those diagnosed, treated, and living with and beyond a cancer diagnosis. Several large prospective studies have enhanced our understanding of how to improve the assessment, treatment, and outcomes of older adults with cancer starting therapy. This article summarizes three recent high-impact trials that produced practice-changing implications for the management of older adults with cancer that led to guideline updates. The key findings from these trials highlight that geriatric assessment-guided interventions in older adults with cancer: (1) facilitated higher rates of chemotherapy completion at planned doses with less modification among patients, (2) reduced grade 3 hematologic and non-hematologic toxicity during treatment delivery among patients of all stages of cancer receiving chemotherapy, and (3) influenced treatment decisions among advanced cancer patients receiving supportive care leading to reduced toxicity through reduced intensity of therapy without compromise of survival.

Indexed as

Geriatric AssessmentGeriatricsMedical OncologyNeoplasmsAgedAntineoplastic AgentsHumansPractice Guidelines as TopicAntineoplastic Agentscancergeriatric assessmentinterdisciplinarytreatment completiontreatment toxicity

Identifiers

PMID39739310
PMCPMC12206927

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.