Evidence map›Paper›PMID 39739162›Full record

ReviewProbiotics and antimicrobial proteins2025

Effects of Probiotics on Liver Diseases: Current In Vitro and In Vivo Studies.

Maryam Sadri, Zahra Shafaghat, Mona Roozbehani, Akram Hoseinzadeh, Fatemeh Mohammadi, Fahimeh Lavi Arab, Sara Minaeian, Soheil Rahmani Fard, Fatemeh Faraji

Abstract readReview
PubMed Publisher
In one paragraph

Review in Probiotics and antimicrobial proteins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Nutrients · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maryam SadriDepartment of Immunology, Iran University of Medical Sciences, Tehran, Iran.
Zahra ShafaghatDepartment of Immunology, Iran University of Medical Sciences, Tehran, Iran.
Mona RoozbehaniVaccine Research Center, Iran University of Medical Sciences, Tehran, Iran.
Akram HoseinzadehCancer Research Center, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
Fatemeh MohammadiDepartment of Immunology, School of Medicine, Mashhad University of Medicine Sciences, Mashhad, Iran.
Fahimeh Lavi ArabDepartment of Immunology, School of Medicine, Mashhad University of Medicine Sciences, Mashhad, Iran.
Sara MinaeianAntimicrobial Resistance Research Center, Institute of Immunology and Infectious Diseases, Iran University of Medicine Sciences, Tehran, Iran.
Soheil Rahmani FardAntimicrobial Resistance Research Center, Institute of Immunology and Infectious Diseases, Iran University of Medicine Sciences, Tehran, Iran.
Fatemeh FarajiAntimicrobial Resistance Research Center, Institute of Immunology and Infectious Diseases, Iran University of Medicine Sciences, Tehran, Iran. faraji.fat@iums.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Various types of liver or hepatic diseases cause the death of about 2 million people worldwide every year, of which 1 million die from the complications of cirrhosis and another million from hepatocellular carcinoma and viral hepatitis. Currently, the second most common solid organ transplant is the liver, and the current rate represents less than 10% of global transplant requests. Hence, finding new approaches to treat and prevent liver diseases is essential. In liver diseases, the interaction between the liver, gut, and immune system is crucial, and probiotics positively affect the human microbiota. Probiotics are a non-toxic and biosafe alternative to synthetic chemical compounds. Health promotion by lowering cholesterol levels, stimulating host immunity, the natural gut microbiota, and other functions are some of the activities of probiotics, and their metabolites, including bacteriocins, can exert antimicrobial effects against a broad range of pathogenic bacteria. The present review discusses the available data on the results of preclinical and clinical studies on the effects of probiotic administration on different types of liver diseases.

Indexed as

Liver DiseasesProbioticsAnimalsGastrointestinal MicrobiomeHumansHepatic diseasesIn vivo and in vitro studiesLiver diseasesProbiotics

Identifiers

PMID39739162

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.