Evidence map›Paper›PMID 39739161›Full record

ReviewProbiotics and antimicrobial proteins2025

The Characterization, Biological Activities, and Potential Applications of the Antimicrobial Peptides Derived from Bacillus spp.: A Comprehensive Review.

Jiaqi Zhang, Xinmiao Yang, Jiajia Qiu, Wen Zhang, Jie Yang, Jinzhi Han, Li Ni

Abstract readReview
PubMed Publisher
In one paragraph

Review in Probiotics and antimicrobial proteins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiaqi Zhang *Food Nutrition and Health Research Center, School of Advanced Manufacturing, Fuzhou University, Jinjiang, 362200, Fujian, China.
Xinmiao Yang *Food Nutrition and Health Research Center, School of Advanced Manufacturing, Fuzhou University, Jinjiang, 362200, Fujian, China.
Jiajia QiuFood Nutrition and Health Research Center, School of Advanced Manufacturing, Fuzhou University, Jinjiang, 362200, Fujian, China.
Wen ZhangFood Nutrition and Health Research Center, School of Advanced Manufacturing, Fuzhou University, Jinjiang, 362200, Fujian, China.
Jie YangJiangsu Key Laboratory of Marine Bioresources and Environment, Jiangsu Ocean University, Lianyungang, 222005, Jiangsu, China.
Jinzhi HanFood Nutrition and Health Research Center, School of Advanced Manufacturing, Fuzhou University, Jinjiang, 362200, Fujian, China. hjz419@fzu.edu.cn.
Li NiFood Nutrition and Health Research Center, School of Advanced Manufacturing, Fuzhou University, Jinjiang, 362200, Fujian, China. nili-fzu@qq.com.

Funding

Fujian Provincial Natural Science Foundation 2024J01360Lianyungang Science and Technology Plan (Basic Research) No. JCYJ2324
6 · The paper itself

Abstract

This paper provides a comprehensive review of antimicrobial peptides (AMPs) derived from Bacillus spp. The classification and structure of Bacillus-derived AMPs encompass a diverse range. There are 89 documented Bacillus-derived AMPs, which exhibit varied sources, amino acid sequences, and molecular structures. These AMPs can be categorized into classes I, Ia, IIa, IIb, IIc, and IId. The synthesis pathway of the AMPs primarily involves either ribosomally synthesized or non-ribosomally synthesized approaches. Additionally, the antimicrobial activity of these AMPs is versatile, targeting bacteria, fungi, and viruses, through disrupting intracellular DNA and the cell wall and membrane, as well as modulating immune responses. Moreover, the Bacillus-derived AMPs demonstrate promising application in the pharmaceutical industry, environmental protection, food preservation, and bio-control in agriculture. The commonly employed strategies for enhancing the production of Bacillus-derived AMPs involve optimizing cultivation conditions, implementing systems metabolic engineering, employing genome shuffling techniques, optimizing promoters, and improving expression host optimization. This review can provide a valuable reference for comprehending the current research status on advancements and sustainable production of Bacillus-derived AMPs.

Indexed as

Antimicrobial PeptidesBacillusAnimalsBacteriaFungiHumansAntimicrobial PeptidesAdvancementAntimicrobial peptidesBacillus spp.ReviewSustainable production

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.