SynthesisClinical oral investigations2024
Platelet-rich fibrin application after mandibular third molar extraction: an umbrella review.
Synthesis in Clinical oral investigations, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Platelet-rich fibrin after mandibular third molar extraction: an umbrella review of systematic reviews and meta-analyses.Oral and maxillofacial surgery · 2026Pooled it
- Modified Coronally Advanced Flaps: A Systematic Review and Meta-Analysis.Dentistry journal · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this study was evaluate the effect of Platelet-Rich Fibrin (PRF) in patients after mandibular third molar extraction through an analysis of the most current literature on systematic reviews and meta-analyses. DATA, SOURCES AND STUDY SELECTION: By using computer-assisted search technology, we comprehensively searched several reliable databases, such as China National Knowledge Infrastructure (CNKI), WanFang Data, the Chinese biomedical literature database, PubMed, Web of Science, EMBase, and the Cochrane Library, and performed a systematic retrospective meta-analysis on all of the collected studies on the therapeutic effects of PRF on patients after mandibular third molar extraction. A total of nine meta-analyses were performed in this study, and all nine studies were rated as high quality on the basis of the AMSTAR 2 criteria. Seven outcome indicators were extracted from the nine meta-analyses.
conclusionAccording to the included studies, which all demonstrated high scientific quality, PRF application after mandibular third molar extraction significantly reduces postoperative pain and inflammation, accelerates soft tissue healing, and effectively lowers the incidence of complications such as dry socket and alveolar osteitis. However, PRF did not significantly affect trismus or bone density. The conclusion has reliable support and clinical significance.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.