Evidence map›Paper›PMID 39739058›Full record

ArticleOral and maxillofacial surgery2024

Factors related to risk of recurrence and recurrence free survival in ameloblastoma of the Jaws: A single centre retrospective analysis.

Rathindra Nath Bera, Preeti Tiwari

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Article in Oral and maxillofacial surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Rathindra Nath BeraSenior Resident Department of Oral and Maxillofacial Surgery, Dental Institute Rajendra Institute of Medical Sciences, Ranchi Jharkhand, 834009, India.ORCID http://orcid.org/0000-0002-4390-3213
Preeti TiwariDepartment of Oral and Maxillofacial Surgery, Faculty of Dental Sciences Institute of Medical Sciences, Banaras Hindu University, Varanasi Uttar Pradesh, 221001, India. drpreetitiwaribhu@gmail.com.ORCID http://orcid.org/0000-0003-0862-7177

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAmeloblastoma is a benign tumor originating from odontogenic epithelium with a global incidence of about 0.5 cases per million persons per year. The overall recurrence rate of ameloblastomas range from 55% -90%. In this retrospective study we have analyzed the factors associated with recurrence and recurrence free survival in ameloblastoma of the jaws.

methodsRetrospective chart review of 10 years was done from records directory. All demographic data, data on diagnostic modalities, clinical presentations, radiology, management and histology were taken into consideration. Kaplan Meir estimator was used to evaluate recurrence rate and Cox regression analysis (univariate and multivariate) was used to evaluate the odds ratio to find out the possible factors influencing risk of recurrence and influence recurrence free survival. ROC curve (Receiver Operating Characteristic) was used to find out the optimal cut off point for size of the lesion in predicting recurrence. A p value of < 0.05 was considered statistically significant at 95% confidence interval.

resultsA total of 75 patients had recurrence with a median follow up of 65 months. The overall 5 year RFS was 19.5%. Conventional ameloblastomas, cortical/ soft tissue invasion, conservative treatment and tumor size ≥ 4 cm were independent predictors of recurrence.

conclusionAggressive treatment is preferred for conventional ameloblastomas ≥ 4 cm with cortical/ soft tissue invasion.

Indexed as

AmeloblastomaJaw NeoplasmsNeoplasm Recurrence, LocalAdolescentAdultAgedChildDisease-Free SurvivalFemaleHumansMaleMiddle AgedNeoplasm InvasivenessRetrospective StudiesRisk FactorsYoung AdultAmeloblastomaJawsRecurrenceRecurrence free survival

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