Evidence map›Paper›PMID 39739048›Full record

ArticleArchives of gynecology and obstetrics2025

Long-term effects of endometrial resection or ablation in combination with levonorgestrel intrauterine device on bleeding patterns.

Signe Engholm Straarup, Ina Isabell Kathleen Heinemeier, Pernille Darre Haahr, Martin Rudnicki

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Article in Archives of gynecology and obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Signe Engholm StraarupDepartment of Obstetrics and Gynecology, Odense University Hospital, Kløvervænget 23, 5000, Odense, Denmark.
Ina Isabell Kathleen HeinemeierDepartment of Obstetrics and Gynecology, Odense University Hospital, Kløvervænget 23, 5000, Odense, Denmark.
Pernille Darre HaahrDepartment of Obstetrics and Gynecology, Odense University Hospital, Kløvervænget 23, 5000, Odense, Denmark.
Martin RudnickiDepartment of Obstetrics and Gynecology, Odense University Hospital, Kløvervænget 23, 5000, Odense, Denmark. mr@rsyd.dk.ORCID 0000-0002-5115-1445

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEndometrial resection and ablation are minimal invasive surgeries used to treat women with abnormal uterine bleeding (AUB). Both may be followed by a high reoperation rate up to 24%. However, some studies suggest that this may be improved by adding a levonorgestrel intrauterine device (LNG-IUD) immediately following surgery. The aim of this studyPl was to evaluate the long-term (12 months) effect of combined LNG-IUD and endometrial resection (TCRE) or ablation (NovaSure) on the rate of amenorrhea in women treated for AUB. STUDY

designThis study was conducted as a prospective cohort study. A total of 119 women answered the questionnaire regarding bleeding patterns 12 months postoperatively and were eligible for statistical analysis.

resultsThe rate of amenorrhea 12 months postoperatively was 11% for TCRE and 58% for TCRE in combination with LNG-IUD (OR 24.71; 95% CI 2.32-262.94; p = 0.008). For the group of women, who underwent NovaSure alone, the incident of amenorrhea 12 months postoperatively was 48, and 62% in combination with an LNG-IUD (OR 1.24; 95% CI 0.34-4.58; p = 0.744).

conclusionOur study disclosed a low effect of TCRE in respect to the amenorrhea rate, whereas the combination with LNG-IUD increased the effect thereby comparable to NovaSure, where no significant beneficial effect was observed from the combination with LNG-IUD.

Indexed as

AmenorrheaEndometrial Ablation TechniquesEndometriumIntrauterine Devices, MedicatedLevonorgestrelMenorrhagiaMetrorrhagiaAdultCombined Modality TherapyContraceptive Agents, FemaleContraceptive Agents, HormonalFemaleHumansMiddle AgedProspective StudiesTreatment OutcomeContraceptive Agents, FemaleContraceptive Agents, HormonalLevonorgestrelAbnormal uterine bleedAmenorrheaHormone-releasing IUDHysterectomyMinimally invasive

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.